{"id":461,"date":"2026-10-19T11:30:00","date_gmt":"2026-10-19T03:30:00","guid":{"rendered":"https:\/\/www.ivd-stage.com\/?p=461"},"modified":"2026-10-18T21:01:14","modified_gmt":"2026-10-18T13:01:14","slug":"20-%e5%88%86%e9%92%9f%e3%80%810-06-%e7%be%8e%e5%85%83%e4%b8%80%e6%ac%a1%ef%bc%8caie%e8%8d%a7%e5%85%89%e5%be%ae%e7%90%83%e6%b5%8bpsa%e8%af%95%e7%ba%b8%e6%9d%a1%e5%81%9a%e5%88%b0%e4%ba%86-0-28-ng-ml","status":"publish","type":"post","link":"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/19\/20-%e5%88%86%e9%92%9f%e3%80%810-06-%e7%be%8e%e5%85%83%e4%b8%80%e6%ac%a1%ef%bc%8caie%e8%8d%a7%e5%85%89%e5%be%ae%e7%90%83%e6%b5%8bpsa%e8%af%95%e7%ba%b8%e6%9d%a1%e5%81%9a%e5%88%b0%e4%ba%86-0-28-ng-ml\/","title":{"rendered":"20 \u5206\u949f\u30010.06 \u7f8e\u5143\u4e00\u6b21\uff0cAIE\u8367\u5149\u5fae\u7403\u6d4bPSA\u8bd5\u7eb8\u6761\u505a\u5230\u4e86 0.28 ng\/mL\uff01"},"content":{"rendered":"<p><!-- IVD-STAGE \u516c\u4f17\u53f7\u6392\u7248\u6a21\u677f\uff08\u5185\u8054\u6837\u5f0f\uff0c\u517c\u5bb9\u5fae\u4fe1\uff09\n\u53d8\u91cf\u5360\u4f4d\u7b26\uff08\u63a8\u9001\u811a\u672c\u4f1a\u66ff\u6362\uff09\uff1a\n  20 \u5206\u949f\u30010.06 \u7f8e\u5143\u4e00\u6b21\uff0cAIE\u8367\u5149\u5fae\u7403\u6d4bPSA\u8bd5\u7eb8\u6761\u505a\u5230\u4e86 0.28 ng\/mL\uff01        \u6587\u7ae0\u6807\u9898\n  [CONTENT]        \u6b63\u6587 HTML\uff08\u7531 markdown \u8f6c\u6362\u5f97\u5230\uff09\n           \u53d1\u5e03\u65e5\u671f 2026\u5e748\u670811\u65e5\n      \u6587\u672b\u7f72\u540d\/\u547c\u544a\uff08\u53ef\u9009\uff09\n  {{RELATED_1..4}} \u5f80\u671f\u63a8\u8350 \u6807\u9898|\u94fe\u63a5 \uff08\u6bcf\u671f\u6362\uff0c\u53ef\u5c11\u586b\uff09\n--><\/p>\n<div style=\"font-family:-apple-system,'PingFang SC','Microsoft YaHei',sans-serif;color:#2b2b2b;font-size:15px;line-height:2;letter-spacing:0.5px;\">\n<p>  <!-- \u6b63\u6587 --><\/p>\n<section style=\"margin:0;padding:16px 8px;background:#f7f8fa;border-radius:8px;\">\n<blockquote style=\"background:#f6f8fb;border-left:4px solid #1f3a5f;margin:14px 0;padding:10px 14px;color:#555;font-size:15px;\"><p>\u6d59\u6c5f\u7701\u519c\u4e1a\u79d1\u5b66\u9662\u4e0e\u4e0a\u6d77\u7406\u5de5\u5927\u5b66\u56e2\u961f\u5728 *Talanta* \u4e0a\u53d1\u4e86\u4e00\u5f20\u805a\u96c6\u8bf1\u5bfc\u53d1\u5149\uff08aggregation-induced emission\uff0cAIE\uff09\u8367\u5149\u5fae\u7403\u4fa7\u5411\u5c42\u6790\u8bd5\u7eb8\u6761\uff0c\u5b9e\u73b0<strong>20 \u5206\u949f<\/strong>\u5b9a\u91cf\u6d4b\u8840\u6e05\u91cc\u7684\u524d\u5217\u817a\u7279\u5f02\u6297\u539f\uff08prostate-specific antigen\uff0cPSA\uff09\uff0c\u68c0\u51fa\u9650 <strong>0.28 ng\/mL<\/strong>\uff0c<strong>40 \u4efd\u8840\u6e05<\/strong>\u6bd4\u5bf9\u5316\u5b66\u53d1\u5149\u514d\u75ab\u5206\u6790\uff08chemiluminescence immunoassay\uff0cCLIA\uff09\u8dd1\u51fa\u7684\u7075\u654f\u5ea6 <strong>96.2%<\/strong>\u3001\u7279\u5f02\u5ea6 <strong>100%<\/strong>\u3001\u4e00\u81f4\u6027 <strong>97.5%<\/strong>\uff0c\u4f5c\u8005\u81ea\u8ff0\u5355\u6b21\u6210\u672c\u7ea6 <strong>0.06 \u7f8e\u5143<\/strong>\u3002<\/p><\/blockquote>\n<p style=\"margin:14px 0;text-align:justify;\"><img decoding=\"async\" src=\"https:\/\/www.ivd-stage.com\/wp-content\/uploads\/2026\/10\/psa_head_20261018.png\" style=\"max-width:100%;border-radius:4px;margin:8px 0;\" alt=\"\"\/><\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u6253\u6cd5<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u4f20\u7edf\u8367\u5149\u6750\u6599\u6709\u4e2a\u8001\u95ee\u9898\uff0c\u6d53\u5ea6\u4e00\u9ad8\u3001\u4e00\u805a\u96c6\u5c31<strong>\u81ea\u6dec\u706d<\/strong>\u3002AIE \u5206\u5b50\u53cd\u8fc7\u6765\uff0c<strong>\u805a\u96c6\u4f53\u8d8a\u6324\u8d8a\u4eae<\/strong>\u3002\u4f5c\u8005\u628a AIE \u5206\u5b50\u5305\u8fdb\u7fa7\u57fa\u5316\u805a\u82ef\u4e59\u70ef\u5fae\u7403\uff0c\u505a\u6210\u4fe1\u53f7\u8f7d\u4f53\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u4e09\u53ea\u5c0f\u9f20\u514d\u75ab\u540e\u6548\u4ef7\u90fd\u8fc7 <strong>1:32000<\/strong>\uff0c\u53d6\u6548\u4ef7\u6700\u9ad8\u7684 2 \u53f7\u9f20\u505a\u878d\u5408\uff0c\u813e\u7ec6\u80de\u4e0e SP2\/0 \u9aa8\u9ad3\u7624\u6309 <strong>7:1<\/strong> \u878d\u5408\uff0c\u95f4\u63a5 ELISA \u7b5b\uff0c<strong>\u56db\u8f6e\u4e9a\u514b\u9686<\/strong>\u62ff\u5230\u7a33\u5b9a\u7ec6\u80de\u682a\uff0c\u518d\u7528\u8179\u6c34\u5236\u5907\u3001Protein G \u7eaf\u5316\uff0c\u5f97\u5230\u4e9a\u578b <strong>IgG1<\/strong>\uff0c\u6548\u4ef7 <strong>1:64000<\/strong>\uff0c\u5bf9\u5b9e\u9a8c\u5ba4\u73b0\u5b58\u7684 <strong>20 \u79cd\u80bf\u7624\u6807\u5fd7\u7269\u65e0\u4ea4\u53c9<\/strong>\uff1b\u514d\u75ab\u7ec4\u5316\u5728\u524d\u5217\u817a\u764c\u7ec4\u7ec7\u80de\u6d46\u91cc\u67d3\u51fa\u68d5\u9ec4\u8272\uff0c\u80c3\u764c\u7ec4\u7ec7\u4e0d\u7740\u8272\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u5fae\u7403\u7ecf EDC\/NHS \u6d3b\u5316\u540e\u6807\u8bb0\u6297\u4f53\uff0c\u6807\u8bb0\u540e\u7c92\u5f84\u4ece <strong>216.7 nm \u6da8\u5230 237.9 nm<\/strong>\uff0czeta \u7535\u4f4d\u4ece <strong>\u221229.4 mV \u5230 \u221224.4 mV<\/strong>\uff0c\u5076\u8054\u6210\u529f\u3002\u8bd5\u7eb8\u6761\u4e0a\uff0cT \u7ebf\u5305\u88ab\u6297 PSA <strong>\u591a\u514b\u9686<\/strong>\u6297\u4f53\uff0cC \u7ebf\u662f\u7f8a\u6297\u9f20 IgG\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u8bfb\u6570\u4ea4\u7ed9\u4e00\u53f0 3D \u6253\u5370\u7684\u4fbf\u643a\u4eea LumiS-1 Pro\uff0c<strong>170\u00d775\u00d760 mm<\/strong>\uff0c365 nm \u6fc0\u53d1\uff0c\u4e1d\u6746\u5e26\u52a8\u6b65\u8fdb\u626b\u63cf\uff0c\u901a\u8fc7\u84dd\u7259\u628a\u7ed3\u679c\u4f20\u9012\u7ed9\u624b\u673a App\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><img decoding=\"async\" src=\"https:\/\/www.ivd-stage.com\/wp-content\/uploads\/2026\/10\/psa_fig1_20261018.png\" style=\"max-width:100%;border-radius:4px;margin:8px 0;\" alt=\"\"\/><\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u6027\u80fd\u8bc4\u4f30<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u4e0a\u6837\u91cf <strong>10 \u03bcL \u8840\u6e05 + 90 \u03bcL Tris-HCl<\/strong>\uff0c\u4f18\u5316\u4e0b\u6765 20 \u5206\u949f\u8bfb\u503c\u6700\u9ad8\uff0c\u5076\u8054 pH <strong>6.0<\/strong>\uff0c\u6297\u4f53\u7528\u91cf <strong>60 \u03bcg<\/strong>\uff0c\u63a2\u9488\u6d53\u5ea6 <strong>0.3 mg\/mL<\/strong>\uff0c\u7f13\u51b2\u6db2 Tris-HCl\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u6807\u51c6\u66f2\u7ebf\u5728 <strong>0.5\u201362.5 ng\/mL<\/strong> \u533a\u95f4\u62df\u5408\u4e3a <strong>y = 0.7165 + 1.4167x + 1.6415x\u00b2<\/strong>\uff0c<strong>R\u00b2 0.9936<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">10 \u4efd\u72ec\u7acb\u9634\u6027\u6837\u672c\u5404\u6d4b\u4e09\u6b21\uff0cT\/C \u5747\u503c <strong>0.1742<\/strong>\u3001\u6807\u51c6\u5dee <strong>0.0637<\/strong>\uff0c\u9608\u503c\u53d6\u5747\u503c\u52a0\u4e09\u500d\u6807\u51c6\u5dee\u5f97 <strong>0.3653<\/strong>\uff1b\u518d\u62ff\u4f4e\u6d53\u5ea6\u6837\u672c\u5f80\u4e0b\u7a00\u91ca\uff0c\u7406\u8bba\u6d53\u5ea6\u4e3a<strong>0.28 ng\/mL<\/strong> \u7684\u6837\u54c1\u54cd\u5e94\u4fe1\u53f7\u503c\u6700\u63a5\u8fd1\u8fd9\u4e2a\u9608\u503c\uff0c\u4e8e\u662f\u5b9a\u5b83\u4e3a\u68c0\u51fa\u9650\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u4e34\u5e8a\u771f\u5b9e\u6837\u54c1\u8bc4\u4ef7<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u4e34\u5e8a\u8bc4\u4ef7\u7528\u4e86 <strong>40 \u4efd\u8840\u6e05<\/strong>\uff1a<strong>26 \u4efd\u6765\u81ea\u524d\u5217\u817a\u764c\u60a3\u8005\uff0c14 \u4efd\u6765\u81ea\u5065\u5eb7\u4eba<\/strong>\uff0c\u53c2\u7167\u65b9\u6cd5\u662f CLIA\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u7ed3\u679c\u53ea\u6709 <strong>1 \u4f8b\u5047\u9634\u6027<\/strong>\uff0c<strong>\u5316\u7597\u4e4b\u540e\u91c7\u96c6\u7684<\/strong>\u3002\u4f5c\u8005\u8ba4\u4e3a\u53ef\u80fd\u4e0e\u60a3\u8005\u4e2a\u4f53\u56e0\u7d20\u6216\u8840\u6e05\u57fa\u8d28\u5e72\u6270\u6709\u5173\uff0c\u9700\u8981\u66f4\u5927\u7684\u961f\u5217\u518d\u67e5\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u603b\u4f53\u7ed9\u51fa\u7684\u7075\u654f\u5ea6 <strong>96.2%<\/strong>\u3001\u7279\u5f02\u5ea6 <strong>100%<\/strong>\u3001\u4e0e CLIA \u4e00\u81f4\u6027 <strong>97.5%<\/strong>\uff1b\u9633\u6027\u7ec4\u4e0e\u9634\u6027\u7ec4\u7684 PSA \u6c34\u5e73\u5dee\u5f02 <strong>P < 0.0001<\/strong>\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u7a33\u5b9a\u6027<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>5 \u4e2a\u6279\u6b21<\/strong>\u7684\u8bd5\u7eb8\u6761\u6d4b\u8bd5 0.5 ng\/mL \u7684 PSA\uff0c\u6279\u95f4 <strong>RSD 7.31%<\/strong>\u3002\u5ba4\u6e29\u5e72\u71e5\u907f\u5149\u5b58\u653e\uff0c<strong>75 \u5929<\/strong>\u68c0\u6d4b\u54cd\u5e94\u6ca1\u6709\u660e\u663e\u53d8\u5316\u3002\u4ea4\u53c9\u53cd\u5e94\u4e0a\uff0c\u4e0e 50 ng\/mL \u7684 CA-153\u3001CA-125\u3001CEA\u3001AFP\u3001NSE\u3001PAP \u65e0\u4ea4\u53c9\u53cd\u5e94\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u201c\u7531\u4e8e\u5176\u9ad8\u7075\u654f\u5ea6\u3001\u4fbf\u643a\u6027\u3001\u667a\u80fd\u5b9a\u91cf\u8bfb\u6570\u548c\u4f4e\u6210\u672c\uff0c\u8be5\u5e73\u53f0\u4e3a\u53bb\u4e2d\u5fc3\u5316\u7684 PSA \u68c0\u6d4b\u548c\u57fa\u5c42\u533b\u7597\u4e0e\u8d44\u6e90\u6709\u9650\u5730\u533a\u7684\u521d\u6b65\u524d\u5217\u817a\u764c\u7b5b\u67e5\uff0c\u63d0\u4f9b\u4e86\u4e00\u4e2a\u6709\u524d\u666f\u7684\u5de5\u5177\u3002\u201d<\/strong><\/p>\n<blockquote style=\"background:#f6f8fb;border-left:4px solid #1f3a5f;margin:14px 0;padding:10px 14px;color:#555;font-size:15px;\"><p>Wu Y, Wang Y, Huang X, Chen G, Gu Y, Wang X, Liu Q. An aggregation-induced emission fluorescent microsphere-based intelligent lateral flow immunosensor for rapid and quantitative detection of prostate-specific antigen. *Talanta*. 2027;313:130766. DOI: 10.1016\/j.talanta.2026.130766\uff08\u5728\u7ebf\u5148\u53d1 2026-10-12\uff1b\u5370\u672c 2027-03\uff09<\/p><\/blockquote>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u514d\u8d23\u58f0\u660e<\/strong><\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u672c\u6587\u57fa\u4e8e\u516c\u5f00\u4fe1\u606f\u4e0e\u5df2\u53d1\u8868\u6587\u732e\u6574\u7406\uff0c\u4ec5\u4ee3\u8868\u4f5c\u8005\u4e2a\u4eba\u89c2\u70b9\uff0c<strong>\u4e0d\u6784\u6210\u4efb\u4f55\u6295\u8d44\u5efa\u8bae<\/strong>\uff1b\u6d89\u53ca\u4e0a\u5e02\u516c\u53f8\u7684\u5185\u5bb9\u5747\u5f15\u81ea\u5176\u516c\u5f00\u62ab\u9732\u6587\u4ef6\uff0c\u4e0d\u4ee3\u8868\u5bf9\u8be5\u516c\u53f8\u8bc1\u5238\u4ef7\u503c\u6216\u7ecf\u8425\u524d\u666f\u7684\u4efb\u4f55\u5224\u65ad\u3002\u6587\u4e2d\u4ea7\u54c1\u4e0e\u6280\u672f\u4fe1\u606f\u4ec5\u4f9b\u884c\u4e1a\u4ea4\u6d41\uff0c<strong>\u4e0d\u6784\u6210\u533b\u7597\u5efa\u8bae\u3001\u8bca\u65ad\u4f9d\u636e\u6216\u4ea7\u54c1\u63a8\u8350<\/strong>\u3002\u5982\u6709\u4e8b\u5b9e\u51fa\u5165\uff0c\u6b22\u8fce\u6307\u6b63\u5e76\u4f9d\u89c4\u66f4\u6b63\u3002<\/p>\n<\/section>\n<p>  <!-- \u6587\u672b\u547c\u544a --><\/p>\n<p style=\"margin:28px 0 8px;color:#1f3a5f;font-weight:bold;font-size:17px;\">\n<p>  <!-- 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style=\"color:#1f6fb8;text-decoration:none;\">\u94fe\u9709\u4eb2\u548c\u7d20\u5fae\u7403\u662f\u5982\u4f55\u5236\u5907\u7684\uff1f<\/a><\/p>\n<p style=\"margin:6px 0;font-size:14px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5NjIzNDU4NQ==&#038;mid=2247484362&#038;idx=1&#038;sn=a68382db7d3008165c534d93125633aa\" style=\"color:#1f6fb8;text-decoration:none;\">\u6297\u4f53\u6807\u8bb0\u7528\u751f\u7269\u7d20\uff0c\u4f60\u9009\u5bf9\u4e86\u5417\uff1f<\/a><\/p>\n<p style=\"margin:6px 0;font-size:14px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5NjIzNDU4NQ==&#038;mid=2247484503&#038;idx=1&#038;sn=69c1df88923335f7cdfa9fdcd84bd519\" style=\"color:#1f6fb8;text-decoration:none;\">\u7a7a\u767d\u9650\u3001\u68c0\u51fa\u9650\u3001\u5b9a\u91cf\u9650\uff0c\u4e00\u7bc7\u5c31\u8ba9\u4f60\u660e\u767d\uff01<\/a><\/p>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>\u6d59\u6c5f\u7701\u519c\u4e1a\u79d1\u5b66\u9662\u4e0e\u4e0a\u6d77\u7406\u5de5\u5927\u5b66\u56e2\u961f\u5728 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