{"id":420,"date":"2026-10-12T07:30:00","date_gmt":"2026-10-11T23:30:00","guid":{"rendered":"https:\/\/www.ivd-stage.com\/?p=420"},"modified":"2026-10-11T21:40:45","modified_gmt":"2026-10-11T13:40:45","slug":"%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf","status":"publish","type":"post","link":"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\/","title":{"rendered":"\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf"},"content":{"rendered":"<p><!-- IVD-STAGE \u516c\u4f17\u53f7\u6392\u7248\u6a21\u677f\uff08\u5185\u8054\u6837\u5f0f\uff0c\u517c\u5bb9\u5fae\u4fe1\uff09\n\u53d8\u91cf\u5360\u4f4d\u7b26\uff08\u63a8\u9001\u811a\u672c\u4f1a\u66ff\u6362\uff09\uff1a\n  \u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf        \u6587\u7ae0\u6807\u9898\n  [CONTENT]        \u6b63\u6587 HTML\uff08\u7531 markdown \u8f6c\u6362\u5f97\u5230\uff09\n           \u53d1\u5e03\u65e5\u671f 2026\u5e748\u670811\u65e5\n      \u6587\u672b\u7f72\u540d\/\u547c\u544a\uff08\u53ef\u9009\uff09\n  {{RELATED_1..4}} \u5f80\u671f\u63a8\u8350 \u6807\u9898|\u94fe\u63a5 \uff08\u6bcf\u671f\u6362\uff0c\u53ef\u5c11\u586b\uff09\n--><\/p>\n<div style=\"font-family:-apple-system,'PingFang SC','Microsoft YaHei',sans-serif;color:#2b2b2b;font-size:15px;line-height:2;letter-spacing:0.5px;\">\n<p>  <!-- \u6b63\u6587 --><\/p>\n<section style=\"margin:0;padding:16px 8px;background:#f7f8fa;border-radius:8px;\">\n<blockquote style=\"background:#f6f8fb;border-left:4px solid #1f3a5f;margin:14px 0;padding:10px 14px;color:#555;font-size:15px;\"><p>\u5c0f\u5206\u5b50\uff08<1000 Da\uff09\u53ea\u6709\u5355\u4e00\u8868\u4f4d\uff0c\u4f20\u7edf\u53ea\u80fd\u505a\u7ade\u4e89\u6cd5\uff1b\u800c<strong>\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53<\/strong>\u80fd\u591f\u8bc6\u522b\u300cAb1\uff0b\u5c0f\u5206\u5b50\u300d\u8fd9\u4e2a\u590d\u5408\u7269\uff0c\u628a\u300c\u4fe1\u53f7\u4e0e\u6d53\u5ea6\u6b63\u76f8\u5173\u300d\u7684\u975e\u7ade\u4e89\u5939\u5fc3\u53d8\u6210\u53ef\u80fd\u3002<\/p><\/blockquote>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u4e00\u3001\u4e3a\u4ec0\u4e48\u9700\u8981\u5b83<\/h2>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">1.1 \u7ade\u4e89\u6cd5\u7684\u56fa\u6709\u7f3a\u9677<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u4e34\u5e8a\u4e0a\u5e38\u89c1\u7684\u6709\uff1a\u96cc\u4e8c\u9187\u3001\u5b55\u916e\u3001\u919b\u56fa\u916e\u300125-\u7f9f\u57fa\u7ef4\u751f\u7d20D\u3001\u4ed6\u514b\u83ab\u53f8\u3001\u73af\u5b62\u9709\u7d20\u7b49\uff0c\u90fd\u662f\u5c0f\u5206\u5b50\u3002\u6839\u636e\u6587\u732e\u62a5\u9053\uff0c\u5176\u7f3a\u70b9\u5927\u81f4\u6709\u4ee5\u4e0b\u51e0\u79cd\u3002<\/p>\n<ul style=\"padding-left:22px;margin:12px 0;\">\n<li style=\"margin:6px 0;\"><strong>\u4e0e\u8d28\u8c31\u4e00\u81f4\u6027\u5dee<\/strong>\u2014\u2014\u540c\u4e00\u6279 <strong>100 \u4efd<\/strong>\u4e34\u5e8a\u6837\u672c\uff0c\u4e09\u5bb6\u56fd\u9645\u54c1\u724c\uff08\u96c5\u57f9\u3001\u8d1d\u514b\u66fc\u3001\u7f57\u6c0f\uff09\u7684\u5316\u5b66\u53d1\u5149\u7ade\u4e89\u6cd5\u6d4b 25-\u7f9f\u57fa\u7ef4\u751f\u7d20D\uff0c\u4e0e LC-MS\/MS \u7684\u4e00\u81f4\u6027\u90fd\u4e0d\u5982\u5939\u5fc3\u6cd5\uff1a\u540e\u8005\u7ebf\u6027\u76f8\u5173\u7cfb\u6570 R \u8fbe\u5230 <strong>0.986<\/strong>\uff0c\u7cbe\u5bc6\u5ea6\u4e5f\u66f4\u4f18\uff08Lanja \u7b49\u7684\u8bc4\u4ef7\uff0c\u89c1 ACS Omega 2024 \u7efc\u8ff0\u5f15\u8ff0\uff09\u3002<\/li>\n<li style=\"margin:6px 0;\"><strong>\u8986\u76d6\u4e0d\u5168\u3001\u6613\u88ab\u7c7b\u4f3c\u7269\u5e72\u6270<\/strong>\u2014\u201425-\u7f9f\u57fa\u7ef4\u751f\u7d20D \u65e2\u8981\u8ba9 25(OH)D\u2082 \u4e0e 25(OH)D\u2083 \u6d4b\u5230\u4e00\u6837\u51c6\uff0c\u53c8\u8981\u5bf9 3-epi-25(OH)D\u2083 \u8fd9\u7c7b\u7ed3\u6784\u7c7b\u4f3c\u7269\u4ea4\u53c9\u7387\u4f4e\uff1b\u539f\u6587\u76f4\u8bf4\u300c\u4f20\u7edf\u7ade\u4e89\u6cd5\u5f80\u5f80\u8fbe\u4e0d\u5230\u8fd9\u4e2a\u6807\u51c6\u300d\u3002<\/li>\n<li style=\"margin:6px 0;\"><strong>\u8bfb\u51fa\u4fe1\u53f7\u4e0e\u5206\u6790\u7269\u6d53\u5ea6\u6210\u53cd\u6bd4<\/strong>\uff0c\u5728\u66f2\u7ebf<strong>\u9ad8\u6d53\u5ea6\u7aef\u96be\u4ee5\u786e\u5b9a\u68c0\u51fa\u9650<\/strong>\u3002<\/li>\n<li style=\"margin:6px 0;\">\u6027\u80fd<strong>\u5b8c\u5168\u4f9d\u8d56\u4e00\u6297\u7684\u7ed3\u5408\u52a8\u529b\u5b66<\/strong>\uff0c\u5206\u6790\u7269\u5fc5\u987b\u6807\u8bb0\uff0c\u4e0e\u7ed3\u6784\u7c7b\u4f3c\u7269\u6709\u4ea4\u53c9\u53cd\u5e94\u5f15\u8d77\u5047\u6027\u53cd\u5e94\u7684\u98ce\u9669\u3002<\/li>\n<\/ul>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">1.2 \u5173\u952e\u524d\u63d0\uff1a\u5c0f\u5206\u5b50\u201c\u80fd\u4e0d\u80fd\u5939\u5fc3\u201d\u53d6\u51b3\u4e8e\u8868\u4f4d\u95f4\u8ddd<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u201c\u5c0f\u5206\u5b50\u505a\u4e0d\u4e86\u5939\u5fc3\u201d\u662f\u5e38\u89c1\u8bef\u89e3<\/strong>\uff0c\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\u7684\u7814\u7a76\u4ece\u4e0a\u4e2a\u4e16\u7eaa\u5c31\u4e00\u76f4\u5728\u8fdb\u884c\u3002Anal Methods 2024 \u7efc\u8ff0\u68b3\u7406\u4e86\u51e0\u5341\u5e74\u7684\u8868\u4f4d\u95f4\u8ddd\u7814\u7a76\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7269\u8d28 P\uff08SP\uff09\uff0c1,347 Da<\/strong>\u2014\u2014\u6297 N \u7aef + C \u7aef\u4e24\u6297\u4f53\uff0cLoD <strong>3 pg\/mL<\/strong>\uff0c\u6bd4\u7ade\u4e89\u6cd5\u7075\u654f \u2265100 \u500d\uff08Cr\u00e9minon 1995\uff09\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u8840\u7ba1\u7d27\u5f20\u7d20 II\uff0c1,048 Da\uff08\u4ec5 8 \u4e2a\u6c28\u57fa\u9178\uff09<\/strong>\u2014\u2014N \u7aef + C \u7aef\u4e24\u6297\u4f53\uff0cLoD <strong>24 pg\/mL<\/strong>\uff0c\u4e0e\u964d\u89e3\u4ea7\u7269\u65e0\u4ea4\u53c9\uff08Grassi\uff09\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7ec4\u80fa\uff0b\u9ad8\u9999\u8349\u9178\u6a21\u578b<\/strong>\u2014\u2014<strong>\u226510 \u4e2a\u4e9a\u7532\u57fa<\/strong>\u624d\u6709\u6548\uff0c8 \u4e2a\u660e\u663e\u4e0b\u964d\uff1b<strong>5 \u00c5 \u53ef\u80fd\u662f\u6709\u4fe1\u53f7\u7684\u6700\u5c0f\u95f4\u8ddd\uff0c>11.5 \u00c5 \u6700\u4f18<\/strong>\uff08Quinton 2010\uff09\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u534a\u5361\u5df4\u80bc\uff08SEM\uff09<\/strong>\u2014\u2014<strong>12 \u00c5 \u8d85\u9608\u503c\uff0c16 \u00c5 \u8fbe\u5e73\u53f0<\/strong>\uff1b\u5939\u5fc3 ELISA \u7075\u654f\u5ea6\u63d0\u9ad8 <strong>30 \u500d<\/strong>\uff0c\u4ea4\u53c9\u7387 <1%\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u4e09\u805a\u6c30\u80fa\uff0b\u5bf9\u785d\u57fa\u82ef\u80fa\uff0c304 Da<\/strong>\u2014\u2014<strong>2.4 \u00c5 \u4ecd\u53ef\u88ab\u4e24\u6297\u4f53\u540c\u65f6\u7ed3\u5408\uff1b8.8 \u00c5 \u9ad8\u6982\u7387\uff1b13.9 \u00c5 \u6700\u4f18<\/strong>\uff08Bai 2022\uff09\uff1b13.9 \u00c5 \u4e0b\u5939\u5fc3 LoD 0.00035 nM vs \u7ade\u4e89 0.001 nM\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u4ed6\u514b\u83ab\u53f8\uff0c804 Da<\/strong>\u2014\u2014\u4e24\u8868\u4f4d\u95f4\u9694 10 \u4e2a\u78b3\uff1bLoD 0.8 ng\/mL\uff1b55 \u4efd\u5168\u8840\u4e0e LC-MS\/MS r=0.991\uff08Siemens\uff09\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u8fbe\u6c99\u66ff\u5c3c\uff0c488 Da<\/strong>\u2014\u2014\u7ea6 2.7 \u00c5\uff1b\u4e24\u5154\u6297\u4f53\u5939\u5fc3\uff0cLOQ <strong>320 pg\/mL<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u963f\u7ef4\u83cc\u7d20\uff0c873 Da<\/strong>\u2014\u2014\u9009 6.3 \u00c5 \u8868\u4f4d A\/B\uff1b<strong>735 \u79cd\u6297\u4f53\u7ec4\u5408\uff0c\u5939\u5fc3\u6210\u529f\u7387\u4ec5 0.27%<\/strong>\uff08Fei 2023\uff09\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u56e0\u6b64\uff0c\u8868\u4f4d\u95f4\u8ddd\u591f\uff08\u5927\u7ea6 \u22655 \u00c5\uff0c>11.5 \u00c5 \u66f4\u7a33\uff09\u65f6\uff0c<strong>\u201c\u8868\u4f4d\u5b9a\u5411\u53cc\u6297\u4f53\u5939\u5fc3\u201d\u786e\u5b9e\u53ef\u884c<\/strong>\uff0c\u4f46<strong>\u6297\u4f53\u914d\u5bf9\u6210\u529f\u7387\u6781\u4f4e\uff080.27%\uff09<\/strong>\uff1b\u95f4\u8ddd\u4e0d\u591f\u65f6\uff0c<strong>\u4e0d\u8981\u6c42\u4e24\u4e2a\u6297\u4f53\u5206\u522b\u7ed3\u5408\u5c0f\u5206\u5b50\u7684\u4e24\u4e2a\u8868\u4f4d\uff0c\u800c\u662f\u8ba9\u7b2c\u4e8c\u4e2a\u6297\u4f53\u53bb\u54ac\u201c\u7b2c\u4e00\u4e2a\u6297\u4f53\uff0b\u5c0f\u5206\u5b50\u201d\u8fd9\u4e2a\u590d\u5408\u7269\u672c\u8eab<\/strong>\u2014\u2014\u8fd9\u5c31\u662f anti-IC\u3002<\/p>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">1.3 anti-IC \u7684\u5b9a\u4f4d<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\uff08anti-immunocomplex antibody, anti-IC\uff09<\/strong>\uff0cVoss \u547d\u540d\u4f53\u7cfb\u91cc\u79f0 <strong>anti-metatype antibody\uff08\u6297 metatype \u6297\u4f53\uff09<\/strong>\uff0c\u5373<strong>\u5bf9\u6e38\u79bb\u534a\u6297\u539f\u548c\u672a\u7ed3\u5408\u7684\u6297\u4f53\u90fd\u6ca1\u6709\u7279\u5f02\u6027\uff0c\u53ea\u8bc6\u522b\u201cAb1\uff0b\u5c0f\u5206\u5b50\u201d\u590d\u5408\u7269<\/strong>\u3002\u5176\u4f18\u70b9\u5728\u4e8e\uff0c<\/p>\n<ul style=\"padding-left:22px;margin:12px 0;\">\n<li style=\"margin:6px 0;\"><strong>\u4fe1\u53f7\u4e0e\u6d53\u5ea6\u6b63\u76f8\u5173<\/strong>\uff1b<\/li>\n<li style=\"margin:6px 0;\"><strong>\u7528\u4e24\u4e2a\u6297\u4f53<\/strong>\uff0c\u964d\u4f4e\u7ed3\u6784\u7c7b\u4f3c\u7269\u4ea4\u53c9\u53cd\u5e94\u98ce\u9669\uff1b<\/li>\n<li style=\"margin:6px 0;\"><strong>\u4e0d\u9700\u8981\u6807\u8bb0\u5206\u6790\u7269<\/strong>\uff0c\u6807\u8bb0\u95e8\u69db\u4f4e\uff1b<\/li>\n<li style=\"margin:6px 0;\">\u975e\u7ade\u4e89\u53cd\u5e94\u6a21\u5f0f\uff0c\u514d\u75ab\u53cd\u5e94\u52a8\u529b\u5b66\u66f4\u597d\uff1b<\/li>\n<li style=\"margin:6px 0;\"><strong>anti-IC \u6297\u4f53\u4e0d\u9700\u8981\u9ad8\u6d53\u5ea6<\/strong>\u5373\u53ef\u6539\u5584\u52a8\u529b\u5b66\uff0c\u964d\u4f4e\u975e\u7279\u5f02\u80cc\u666f\u3001\u8fdb\u4e00\u6b65\u538b\u4f4e\u4ea4\u53c9\u53cd\u5e94\u3002<\/li>\n<\/ul>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u4e8c\u3001\u673a\u5236\u57fa\u7840<\/h2>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">2.1 \u5c0f\u5206\u5b50\u7ed3\u5408\u4f1a\u5f15\u8d77\u6297\u4f53\u6784\u8c61\u6539\u53d8<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">ACS Omega 2024 \u7efc\u8ff0\u6c47\u603b\uff1a<\/p>\n<ul style=\"padding-left:22px;margin:12px 0;\">\n<li style=\"margin:6px 0;\">\u5c0f\u5206\u5b50\u4e0e\u6d3b\u6027\u4f4d\u70b9\u7ed3\u5408<strong>\u8bf1\u5bfc\u6297\u4f53\u6784\u8c61\u53d8\u5316<\/strong>\uff08N\u00e9meth \u7684 FITC\/IgG1 \u5149\u8c31\u7814\u7a76\uff1a\u7ed3\u5408\u540e<strong>\u53ef\u53d8\u533a\u4e0e FITC \u4e4b\u95f4\u7684\u6c34\u5408\u5ea6\u663e\u8457\u4e0b\u964d<\/strong>\uff0c\u6539\u53d8\u5206\u5b50\u8fd0\u52a8\uff1b\u4e14\u53d8\u5316<strong>\u4e0d\u9650\u4e8e CDR\uff0c\u6052\u5b9a\u533a\u4e5f\u53d1\u751f\u53d8\u5316<\/strong>\uff09\u3002<\/li>\n<li style=\"margin:6px 0;\">Fab \u6bcf\u6761\u80bd\u94fe\u7ea6 <strong>230 \u4e2a\u6c28\u57fa\u9178<\/strong>\uff0c6 \u4e2a CDR \u5171\u7ea6 <strong>70 \u4e2a\u6b8b\u57fa<\/strong>\uff0c\u6784\u6210\u7ea6 <strong>2,800 \u00c5\u00b2 \u7684\u8fde\u7eed\u8868\u9762<\/strong>\u3002<\/li>\n<li style=\"margin:6px 0;\"><strong>CDR3 \u6700\u67d4\u6027<\/strong>\uff0c\u6297\u539f\u7ed3\u5408\u65f6\u5e38\u53d1\u751f\u663e\u8457\u6784\u8c61\u53d8\u5316\uff0c\u5bfc\u81f4\u7ed3\u5408\u53e3\u888b<strong>\u5f62\u6210\u6216\u95ed\u5408<\/strong>\uff08induced fit \/ \u5f02\u6784\u5316\u673a\u5236\uff09\u3002<\/li>\n<\/ul>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>Qaraghuli \u5f52\u7eb3\u7684\u4e09\u79cd\u7ed3\u5408\u9762\u884c\u4e3a<\/strong>\uff1a<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">1. <strong>\u7ed3\u5408\u540e\u5f62\u6210\u53e3\u888b<\/strong>\u2014\u2014\u6700\u6709\u5229\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">2. <strong>\u7ed3\u5408\u540e\u53e3\u888b\u6d88\u5931<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">3. <strong>\u53e3\u888b\u4e0d\u53d8\u6216\u51e0\u4e4e\u4e0d\u53d8<\/strong>\u2014\u2014\u4f7f\u6297\u4f53\u7b5b\u9009\u53d8\u5f97\u66f4\u4e3a\u56f0\u96be\u3002<\/p>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">2.2 anti-IC \u8bc6\u522b\u7684\u662f\u6784\u8c61\u8868\u4f4d<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>anti-IC \u8bc6\u522b\u7684\u8868\u4f4d\u7531\u300c\u5c0f\u5206\u5b50 + Ab1 \u53ef\u53d8\u533a\u300d\u5171\u540c\u6784\u6210\uff0c\u662f\u6784\u8c61\u8868\u4f4d\uff0c\u4e0d\u662f\u7ebf\u6027\u6c28\u57fa\u9178\u5e8f\u5217\u3002<\/strong><\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u6297\u4f53\u7ed3\u5408\u540e\uff0c\u5c0f\u5206\u5b50\u7684\u4e00\u7ea7\u89e3\u79bb\u901f\u7387\u88ab\u663e\u8457\u62d6\u6162\uff0c\u6709\u7814\u7a76\u8ba4\u4e3a\u673a\u5236\u53ef\u80fd\u662f Ab1 \u53ef\u53d8\u533a\u632f\u52a8\u52a8\u529b\u5b66\u88ab\u5927\u5e45\u538b\u4f4e\uff0c\u800c\u4e0d\u53ea\u662f\u7a7a\u95f4\u4f4d\u963b\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u4e09\u3001\u5236\u5907\u8def\u7ebf<\/h2>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u8def\u7ebf 1\uff1a\u4f20\u7edf\u52a8\u7269\u514d\u75ab + \u6742\u4ea4\u7624<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u7528\u300c\u6297\u5c0f\u5206\u5b50\u6297\u4f53\uff08Ab1\uff09\uff0b\u5c0f\u5206\u5b50\u300d\u9884\u5148\u5f62\u6210\u7684<strong>\u590d\u5408\u7269<\/strong>\u5f53\u514d\u75ab\u539f\uff0c\u8ba9\u514d\u75ab\u7cfb\u7edf\u628a\u590d\u5408\u7269\u4e0a\u7684\u65b0\u6784\u8c61\u9762\u5f53\u505a\u201c\u5f02\u5df1\u201d\uff0c\u523a\u6fc0\u6297\u4f53\u4ea7\u751f\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u53c2\u8003 Towbin 1995 \u5e74\u7684\u7814\u7a76\u8bba\u6587\uff08\u8840\u7ba1\u7d27\u5f20\u7d20 II\uff0cA-II\uff09\uff0c\u5927\u81f4\u5206\u4e3a\u4ee5\u4e0b\u51e0\u4e2a\u6b65\u9aa4\uff1a<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7b2c\u4e00\u6b65\uff1a\u5148\u505a\u51fa mAb1<\/strong><\/p>\n<p style=\"margin:14px 0;text-align:justify;\">A-II \u7ecf <strong>N \u7aef\u8fd8\u539f\u80fa\u5316<\/strong>\u5076\u8054\u5230<strong>\u8fc7\u7898\u9178\u6c27\u5316\u7684 KLH<\/strong>\uff0c\u7ecf\u514d\u75ab\u5c0f\u9f20\uff0cday74 \u540e\u5f97\u5230\u878d\u5408 <strong>PA1 \u9aa8\u9ad3\u7624<\/strong>\u7ec6\u80de\uff0c\u5206\u79bb\u9274\u5b9a\uff0c\u5f97\u5230\u9633\u6027\u514b\u9686 <strong>mAb1<\/strong>\uff1b<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7b2c\u4e8c\u6b65\uff1a\u628a\u590d\u5408\u7269\u4ea4\u8054\u56fa\u5b9a<\/strong><\/p>\n<p style=\"margin:14px 0;text-align:justify;\">A-II 20 \u00b5g + mAb1 78.17 1 mg + KLH 1 mg\uff0c\u6eb6\u4e8e 1 mL PBS \u4f5c\u4e3a\u53cd\u5e94\u4f53\u7cfb\uff0c3 \u4efd 10 \u00b5L \u620a\u4e8c\u919b\uff082.5% w\/v\uff09\u4f5c\u4e3a\u4ea4\u8054\u5242\uff0c\u6bcf 5 \u5206\u949f\u52a0\u4e00\u4efd\uff0c\u52a0 10 \u00b5L 1 M \u7518\u6c28\u9178\u7ec8\u6b62\u53cd\u5e94\uff0c\u5206\u79bb\u7eaf\u5316\u540e\u5f97\u5230<strong>\u514d\u75ab\u590d\u5408\u7269\uff08IC\uff09<\/strong>\uff1b<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7b2c\u4e09\u6b65\uff1a\u83b7\u53d6 anti-IC<\/strong><\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u5c06\u514d\u75ab\u590d\u5408\u7269\u514d\u75ab\u5c0f\u9f20\uff0c\u83b7\u5f97\u9aa8\u9ad3\u7624\u7ec6\u80de\uff0c\u5206\u79bb\u9274\u5b9a\uff0c\u5f97\u5230\u9633\u6027\u514b\u9686\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u5316\u5b66\u4ea4\u8054\u65b9\u6cd5\u4e0d\u6b62\u620a\u4e8c\u919b\u6cd5\uff0c\u5e38\u7528\u7684 <strong>NHS \u916f\u6cd5\u3001EDC \u6cd5<\/strong>\u7b49\u90fd\u53ef\u4ee5\u5c1d\u8bd5\uff0c\u4f46\u65e0\u8bba\u4f55\u79cd\u65b9\u6cd5\uff0c<strong>\u4ecd\u6709\u76f8\u5f53\u6bd4\u4f8b\u4ea7\u7269\u662f\u6297 Ab1 \u7684\u7279\u5f02\u6027\u6297\u4f53<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u8fd9\u6761\u4f20\u7edf\u8def\u7ebf\u7684\u7f3a\u70b9\u662f\uff0c\u9633\u6027\u7387\u8f83\u4f4e\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u5f53\u7136\uff0c\u4ee5\u5f53\u524d\u5355 B \u7ec6\u80de\u6297\u4f53\u6280\u672f\uff0c\u53ef\u4ee5\u5b9e\u73b0\u6297\u4f53\u7684\u76f4\u63a5\u8868\u8fbe\uff0c\u800c\u65e0\u987b\u6742\u4ea4\u7624\u7cfb\u7edf\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u8def\u7ebf 2\uff1a\u566c\u83cc\u4f53\u5c55\u793a\u6297\u4f53\u5e93<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u76f8\u6bd4\u4f20\u7edf\u514d\u75ab\uff0c\u566c\u83cc\u4f53\u5c55\u793a\u53ef\u7cbe\u786e\u63a7\u5236\u7b5b\u9009\u6761\u4ef6\uff0c\u56e0\u800c\u80fd\u9488\u5bf9\u201c\u7a33\u5b9a\u6027\u6709\u9650\u7684\u5206\u5b50\u590d\u5408\u7269\u201d\u4ea7\u751f\u6297\u4f53\uff08B\u00e4ckstr\u00f6m 2026 \u539f\u6587\u660e\u786e\u5199\u51fa\u8fd9\u4e00\u70b9\uff09\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u5e38\u7528\u6297\u4f53\u5e93\u6709\uff1a<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7eb3\u7c73\u6297\u4f53\u514d\u75ab\u5e93<\/strong>\u2014\u20143\u20135 \u4e2a\u6708\uff0c\u5f62\u5f0f VHH\uff0c\u7b5b\u9009\u901a\u91cf 10\u2078\u201310\u2079\uff0c\u4eb2\u548c\u529b nM\u2013pM\uff1b\u4f18\u52bf\u662f\u53ef\u505a\u4eb2\u548c\u6210\u719f\u3001\u9ad8\u4eb2\u548c\u9ad8\u7279\u5f02\uff0c\u5c40\u9650\u662f\u5e93\u5bb9\u5c0f\u3001\u53d7\u6297\u539f\u7279\u6027\u5f71\u54cd\u3001<strong>\u6bcf\u79cd\u6297\u539f\u9700\u5355\u72ec\u5efa\u5e93<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7eb3\u7c73\u6297\u4f53\u5929\u7136\u5e93<\/strong>\u2014\u20142\u20134 \u4e2a\u6708\uff0c\u5f62\u5f0f VHH\uff0c\u7b5b\u9009\u901a\u91cf 10\u00b9\u2070\u201310\u00b9\u00b2\uff0c\u4eb2\u548c\u529b \u03bcM\u2013nM\uff1b\u4f18\u52bf\u662f<strong>\u4e0d\u9700\u514d\u75ab<\/strong>\u3001\u5e93\u5bb9\u5927\u3001\u53ef\u9488\u5bf9\u6240\u6709\u5929\u7136\u6297\u539f\uff0c\u5c40\u9650\u662f\u7279\u5f02\u6027\u4f4e\u3001\u7b5b\u9009\u6548\u7387\u4f4e\u3001\u591a\u6837\u6027\u4e0d\u8db3\u3001<strong>\u4eb2\u548c\u529b\u672a\u6210\u719f<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>scFv \u5408\u6210\u5e93<\/strong>\u2014\u20142\u20134 \u4e2a\u6708\uff0c\u5f62\u5f0f ScFv\uff0c\u7b5b\u9009\u901a\u91cf 10\u00b9\u00b9\u201310\u00b9\u00b3\uff0c\u4eb2\u548c\u529b nM\u2013pM\uff1b\u4f18\u52bf\u662f CDR3 \u5e8f\u5217\u968f\u673a\u3001\u957f\u5ea6\u591a\u6837\u3001\u53ef\u6a21\u62df\u4eb2\u548c\u6210\u719f\uff0c\u5c40\u9650\u662f<strong>\u8f7b\u91cd\u94fe\u975e\u5929\u7136\u914d\u5bf9<\/strong>\u3001\u5efa\u5e93\u6210\u672c\u9ad8\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u53c2\u8003 B\u00e4ckstr\u00f6m et al. \u4e8e 2026 \u5e74\u53d1\u8868\u5728 Anal Chem \u4e0a\u7684\u8bba\u6587\uff08\u777e\u916e anti-IC \u6297\u4f53\uff09\uff0c\u5927\u81f4\u6b65\u9aa4\u6709\uff1a<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">1. <strong>\u53bb\u6742<\/strong>\u2014\u2014\u566c\u83cc\u4f53\u5148\u8ddf mAb 77\uff08\u56fa\u5b9a\u5728\u677f\u6216\u78c1\u73e0\u4e0a\uff09\u5b75\u80b2 1 h\uff0c<strong>\u53ea\u53d6\u6ca1\u7ed3\u5408\u4e0a\u53bb\u7684\u90e8\u5206<\/strong>\u8fdb\u5165\u4e0b\u4e00\u6b65\uff08\u4ece\u7b2c 2 \u8f6e\u5f00\u59cb\uff09\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">2. <strong>\u6311\u590d\u5408\u7269<\/strong>\u2014\u2014\u5269\u4e0b\u7684\u566c\u83cc\u4f53\u53bb\u7ed3\u5408\u201c<strong>mAb 77 \uff0b \u777e\u916e<\/strong>\u201d\u7684\u590d\u5408\u7269\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">3. <strong>\u6d17\u6389\u5f31\u7ed3\u5408<\/strong>\u2014\u2014\u6bcf\u8f6e<strong>\u52a0\u5927\u6d17\u6da4\u529b\u5ea6<\/strong>\uff0c\u5e76<strong>\u51cf\u5c11 mAb 77 \u7528\u91cf<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u6bcf\u8f6e\u6362\u4e00\u79cd\u56fa\u76f8<\/strong>\uff0c\u9632\u6b62\u7b5b\u5230\u5047\u9633\u6027\uff1a\u7b2c 1 \u8f6e\u5171\u4ef7\u5076\u8054\u5230 <strong>Tosyl \u6d3b\u5316\u78c1\u73e0<\/strong>\uff1b\u7b2c 2 \u8f6e\u751f\u7269\u7d20\u5316 \uff0b <strong>\u94fe\u9709\u4eb2\u548c\u7d20\u78c1\u73e0\uff08MyOne C1\uff09<\/strong>\uff1b\u7b2c 3\u30014 \u8f6e\u751f\u7269\u7d20\u5316 \uff0b <strong>avidin \u5305\u88ab\u78c1\u73e0\uff08M-270 Epoxy\uff09<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u7b2c 4 \u8f6e\u540e\u628a\u5bcc\u96c6\u5e93\u514b\u9686\u8fdb\u8868\u8fbe\u8f7d\u4f53\uff0c\u505a\u6210 <strong>Fab-\u78b1\u6027\u78f7\u9178\u9176\uff08AP\uff09\u878d\u5408\u86cb\u767d<\/strong>\uff0c\u8f6c\u5316\u5927\u80a0\u6746\u83cc\uff0c<strong>\u6311\u51fa 95 \u4e2a\u514b\u9686<\/strong>\u8fdb\u884c\u7b5b\u9009\uff0c<strong>\u7ed3\u679c<\/strong>\u6700\u4f18\u514b\u9686 <strong>Fab G9<\/strong>\uff0c\u7528\u4e8e\u975e\u7ade\u4e89 TRF \u514d\u75ab\u5206\u6790\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u8def\u7ebf 3\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u80bd\uff08PHAIA \/ AIcP\uff09<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u7528\u566c\u83cc\u4f53\u5c55\u793a\u80bd\u66ff\u4ee3 anti-IC \u6297\u4f53\uff0c\u4e25\u683c\u8bb2\u8fd9\u6761\u8def\u7ebf\u4ea7\u51fa\u7684\u4e0d\u662f\u6297\u4f53\u800c\u662f\u80fd\u591f\u7279\u5f02\u6027\u7ed3\u5408\u7684<strong>\u80bd<\/strong>\uff0c\u4f46\u5728\u5c0f\u5206\u5b50\u5939\u5fc3\u91cc\u5730\u4f4d\u4e0e anti-IC \u6297\u4f53\u5e76\u5217\u3002<\/p>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">3.1 \u4e3a\u4ec0\u4e48\u80fd\u884c<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">1. \u9009\u51fa\u7684\u566c\u83cc\u4f53\u80bd\u80fd<strong>\u8bc6\u522b\u6297\u4f53\u7ed3\u5408\u53e3\u888b\u5728\u7ed3\u5408\u5206\u6790\u7269\u540e\u5f15\u8d77\u7684\u6784\u8c61\u53d8\u5316<\/strong>\uff1b<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">2. <strong>\u566c\u83cc\u4f53\u9897\u7c92\u8868\u9762\u7531 >2,700 \u62f7\u8d1d\u7684 pVIII \u4e3b\u8981\u5916\u58f3\u86cb\u767d\u6784\u6210<\/strong>\uff0c\u4f5c\u4e3a<strong>\u9ad8\u591a\u4ef7\u652f\u67b6<\/strong>\u7ed3\u5408\u6297\u566c\u83cc\u4f53\u6297\u4f53-HRP\uff0c\u80fd\u5b9e\u73b0<strong>\u4fe1\u53f7\u653e\u5927<\/strong>\uff1b<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">3. PHAIA \u7075\u654f\u5ea6\u4f18\u4e8e\u5316\u5b66\u5408\u6210\u7ade\u4e89\u534a\u6297\u539f ELISA\u3002<\/p>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">3.2 \u80bd\u5e93\u7c7b\u578b<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u6839\u636e\u6587\u732e\u62a5\u9053\uff0c\u5217\u4e3e\u5982\u4e0b\uff1a<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u73af\u72b6\u968f\u673a 7\/8\/9\/10 \u6c28\u57fa\u9178\u6df7\u5408\u5e93<\/strong>\u2014\u2014\u5357\u4eac\u519c\u4e1a\u5927\u5b66\u6784\u5efa\uff08You 2022\uff09\uff0cCui 2025\u3001Gao 2025 \u7528\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>NEB Ph.D.-C7C \u73af\u4e03\u80bd\u5e93<\/strong>\u2014\u2014\u5546\u54c1\u5e93\uff0cFu \u7528\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u73af\u72b6\u968f\u673a\u516b\u80bd\u5e93<\/strong>\uff08M13KE \u8f7d\u4f53\uff09\u2014\u2014<strong>\u591a\u6837\u6027 3.4\u00d710\u00b9\u00b3 \u72ec\u7acb\u514b\u9686<\/strong>\uff1b\u80bd\u4e24\u4fa7\u4e3a\u534a\u80f1\u6c28\u9178\uff0c\u8fde\u63a5\u4e8e <strong>pIII \u4e3b\u8981\u5916\u58f3\u86cb\u767d N \u7aef<\/strong>\uff0cDong \u7528\u3002<\/p>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">3.3 \u6dd8\u9009\uff08biopanning\uff09<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u53c2\u8003 Gao 2025 \u5e74\u53d1\u8868\u7684\u8bba\u6587\uff0c\u8fc7\u7a0b\u5982\u4e0b\uff1a<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">1. \u677f\u6d17 5 \u6b21\uff081\u2030 PBST\uff09<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">2. <strong>3% \u8131\u8102\u5976\u7c89 \/ PBS \u5c01\u95ed\uff0c37 \u00b0C 2 h<\/strong>\uff0c\u518d\u6d17 5 \u6b21<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">3. \u8bbe<strong>\u7ade\u4e89\u5b54<\/strong> 3 \u4e2a\uff1a\u52a0\u6df7\u5408\u80bd\u5e93 100 \u00b5L\/\u5b54\uff08\u7a00\u91ca\u81f3 <strong>1\u00d710\u2079 pfu\/\u00b5L<\/strong>\uff0c5% \u8131\u8102\u5976\u7c89\uff09<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">4. \u8bbe<strong>\u975e\u7ade\u4e89\u5b54<\/strong> 3 \u4e2a\uff1a\u52a0<strong>\u5206\u6790\u7269\u6807\u51c6\u6db2\uff0810 \u00b5g\/mL\uff09<\/strong> 100 \u00b5L\/\u5b54\uff0c\u5ba4\u6e29 1 h<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">5. <strong>\u4ece\u672a\u7ed3\u5408\u7684\u7ade\u4e89\u5b54\u4e2d\u628a\u566c\u83cc\u4f53\u8f6c\u79fb\u5230\u975e\u7ade\u4e89\u5b54<\/strong>\uff0c\u5ba4\u6e29 1 h<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">6. <strong>1\u2030 PBST \u6d17 10 \u6b21<\/strong><\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u5176\u672c\u8d28\u539f\u7406\u90fd\u662f<strong>\u5148\u7528\u201c\u7a7a\u8f7d\u6297\u4f53\u201d\u5438\u9644\u6389\u6742\u566c\u83cc\u4f53\uff0c\u518d\u628a\u5269\u4f59\u90e8\u5206\u4ea4\u7ed9\u201c\u5df2\u7ed3\u5408\u5206\u6790\u7269\u7684\u6297\u4f53\u201d<\/strong>\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u8def\u7ebf 4\uff1aADLib\uff08\u81ea\u4e3b\u591a\u6837\u5316\u6587\u5e93\uff09<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>Autonomously Diversifying Library<\/strong>\uff0c\u53c2\u8003 Seo H. et al. *Nat Protoc* 2006\u3002<\/p>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">4.1 \u539f\u7406<\/h2>\n<ul style=\"padding-left:22px;margin:12px 0;\">\n<li style=\"margin:6px 0;\">\u7528<strong>\u9e21 DT40 B \u7ec6\u80de\u7cfb<\/strong>\uff0c\u5b83\u7684<strong>\u8f7b\u94fe\u548c\u91cd\u94fe Ig \u4f4d\u70b9\u90fd\u5929\u7136\u53d1\u751f\u7ec4\u6210\u578b\u57fa\u56e0\u8f6c\u6362\uff08gene conversion\uff09<\/strong>\uff0c\u8fd9\u662f\u9e21\u7b49\u52a8\u7269 Ig \u57fa\u56e0\u521d\u7ea7\u591a\u6837\u5316\u7684\u673a\u5236\uff1b<\/li>\n<li style=\"margin:6px 0;\">\u7528<strong>\u7ec4\u86cb\u767d\u53bb\u4e59\u9170\u5316\u9176\u6291\u5236\u5242 TSA\uff08\u66f2\u53e4\u6291\u83cc\u7d20 A\uff09<\/strong>\u5904\u7406\u7ec6\u80de\uff0c\u4f7f\u7ec4\u86cb\u767d\u4e59\u9170\u5316\uff0c\u5bfc\u81f4\u67d3\u8272\u8d28\u53ef\u53ca\u6027\u4e0a\u5347\uff0c\u5f15\u8d77 Ig \u4f4d\u70b9\u57fa\u56e0\u8f6c\u6362\u9891\u7387\u88ab\u6fc0\u6d3b\uff0c\u7ec6\u80de\u81ea\u4e3b\u6f14\u5316\u51fa\u591a\u6837\u5316\u6587\u5e93\uff08ADLib\uff09\uff0c\u800c\u6bcf\u4e2a\u7ec6\u80de\u8868\u9762 IgM \u7684\u7279\u5f02\u6027\u90fd\u4e0d\u540c\u3002<\/li>\n<li style=\"margin:6px 0;\">DT40 <strong>\u540c\u65f6\u4ea7\u819c\u7ed3\u5408\u578b\u4e0e\u5206\u6ccc\u578b IgM<\/strong>\uff0c\u6240\u4ee5\u80fd\u7528<strong>\u6297\u539f\u5076\u8054\u78c1\u73e0<\/strong>\u76f4\u63a5\u9009\u51fa\u6297\u539f\u7279\u5f02\u7684\u6d3b\u7ec6\u80de\uff0c\u518d\u7528\u57f9\u517b\u4e0a\u6e05\u91cc\u7684\u5206\u6ccc\u578b\u6297\u4f53\u505a\u68c0\u6d4b\u3002<\/li>\n<\/ul>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">4.2 \u64cd\u4f5c\u6b65\u9aa4\uff08\u539f\u6587\u6d41\u7a0b\uff0c\u53ef\u76f4\u63a5\u7167\u505a\uff09<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7b2c 1 \u6b65\uff1a\u5efa\u5e93<\/strong><\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u8fd9\u4e00\u6b65\u5fc5\u987b\u76d1\u6d4b\u57fa\u56e0\u8f6c\u6362\u662f\u5426\u771f\u88ab\u6fc0\u6d3b\uff0c\u7528 CL18 \u7ec6\u80de\u505a\u56de\u590d\u7a81\u53d8\u8bd5\u9a8c\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7b2c 2 \u6b65\uff1a\u5236\u5907\u6297\u539f\u5076\u8054\u78c1\u73e0\uff08\u86cb\u767d\u6297\u539f\uff09<\/strong><\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7b2c 3 \u6b65\uff1a\u7528\u78c1\u73e0\u4ece\u6587\u5e93\u4e2d\u9009\u7ec6\u80de<\/strong><\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7b2c 4 \u6b65\uff1aELISA \u7b5b\u67e5<\/strong><\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u8be6\u7ec6\u65b9\u6cd5\uff0c\u611f\u5174\u8da3\u7684\u6253\u5de5\u4eba\uff0c\u53ef\u4ee5\u770b\u4e0a\u9762\u7684\u6587\u732e\uff0c\u627e\u4e00\u4e0b\u539f\u6587\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u8def\u7ebf\u5bf9\u6bd4<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u6742\u4ea4\u7624<\/strong>\u2014\u2014\u4f18\u52bf\u662f\u6280\u672f\u6210\u719f\u3001\u7814\u53d1\u6210\u672c\u4f4e\uff1b\u5c40\u9650\u662f<strong>\u7ec6\u80de\u682a\u4e0d\u7a33\u5b9a\u3001\u6548\u7387\u4f4e\u3001\u5468\u671f\u957f<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7eb3\u7c73\u6297\u4f53\u514d\u75ab\u5e93<\/strong>\u2014\u2014\u4f18\u52bf\u662f\u53ef\u505a\u4eb2\u548c\u6210\u719f\u3001\u9ad8\u4eb2\u548c\u9ad8\u7279\u5f02\uff1b\u5c40\u9650\u662f\u5e93\u5bb9\u8f83\u5c0f\u3001\u53d7\u6297\u539f\u7279\u6027\u5f71\u54cd\u3001<strong>\u6bcf\u79cd\u6297\u539f\u9700\u5206\u522b\u5efa\u5e93<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u7eb3\u7c73\u6297\u4f53\u5929\u7136\u5e93<\/strong>\u2014\u2014\u4f18\u52bf\u662f<strong>\u4e0d\u9700\u514d\u75ab<\/strong>\u3001\u5e93\u5bb9\u5927\u3001\u53ef\u9488\u5bf9\u6240\u6709\u5929\u7136\u6297\u539f\uff1b\u5c40\u9650\u662f\u7279\u5f02\u6027\u4f4e\u3001\u7b5b\u9009\u6548\u7387\u4f4e\u3001\u591a\u6837\u6027\u4e0d\u8db3\u3001<strong>\u4eb2\u548c\u529b\u672a\u6210\u719f<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>scFv \u5408\u6210\u5e93<\/strong>\u2014\u2014\u4f18\u52bf\u662f CDR3 \u5e8f\u5217\u968f\u673a\u3001\u957f\u5ea6\u591a\u6837\u3001\u53ef\u6a21\u62df\u4eb2\u548c\u6210\u719f\uff1b\u5c40\u9650\u662f<strong>\u8f7b\u91cd\u94fe\u975e\u5929\u7136\u914d\u5bf9<\/strong>\u3001\u5efa\u5e93\u6210\u672c\u9ad8\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\"><strong>ADLib<\/strong>\u2014\u2014\u4f18\u52bf\u662f\u7b5b\u9009\u5feb\u3001\u9ad8\u4eb2\u548c\u9ad8\u7279\u5f02\u3001<strong>\u6587\u5e93\u591a\u6837\u6027\u9ad8<\/strong>\uff1b\u5c40\u9650\u662f<strong>\u7814\u53d1\u6210\u672c\u9ad8\u3001\u6280\u672f\u590d\u6742<\/strong>\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u56db\u3001\u7b5b\u9009\u5224\u636e\u4e0e\u4f4d\u70b9\u5b9a\u4f4d<\/h2>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u4e09\u6761\u5224\u636e\uff08\u8d2f\u7a7f\u5168\u90e8\u8def\u7ebf\uff09<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u7b5b\u5230\u7684\u5019\u9009\u5fc5\u987b<strong>\u540c\u65f6<\/strong>\u6ee1\u8db3\uff1a<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">1. <strong>\u4e0d\u7ed3\u5408\u6e38\u79bb Ab1<\/strong>\uff08\u7a7a\u8f7d\u6297\u4f53\uff09\uff1b<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">2. <strong>\u4e0d\u7ed3\u5408\u6e38\u79bb\u5c0f\u5206\u5b50<\/strong>\uff1b<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">3. <strong>\u4e0d\u7ed3\u5408\u65e0\u5173\u6297\u4f53<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u5404\u8def\u7ebf\u5177\u6709\u5bf9\u5e94\u7684\u5b9e\u73b0\u624b\u6bb5\u3002<\/p>\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u4f4d\u70b9\u5b9a\u4f4d<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u628a\u5019\u9009\u4f4d\u70b9\u751f\u7269\u7d20\u5316\uff0c\u770b\u7ed3\u5408\u662f\u5426\u6d88\u5931\uff0c\u5373\u53ef\u5224\u65ad anti-IC \u7ed3\u5408\u5728\u590d\u5408\u7269\u7684\u54ea\u4e2a\u4f4d\u7f6e\uff0c\u6587\u732e\u62a5\u9053\u7684\u4f8b\u5b50\u6709\uff1a<\/p>\n<ul style=\"padding-left:22px;margin:12px 0;\">\n<li style=\"margin:6px 0;\"><strong>\u6297 E2 \u7684 anti-IC \u6297\u4f53<\/strong>\uff1aE2 \u7684 <strong>C6 \u4f4d<\/strong>\u88ab\u751f\u7269\u7d20\u5316\u540e\u53cd\u5e94\u51e0\u4e4e\u6d88\u5931 \u2192 \u8bc6\u522b\u590d\u5408\u7269\u4e2d E2 \u7684 <strong>C6 \u4f4d<\/strong>\u533a\u57df\uff1b<\/li>\n<li style=\"margin:6px 0;\"><strong>\u6297 25(OH)D \u7684\u5bf9\u5e94\u6297\u4f53<\/strong>\uff1a<strong>25(OH)D\u2083 \u751f\u7269\u7d20\u5316\u540e\u53cd\u5e94\u53d8\u5f31<\/strong> \u2192 \u8bc6\u522b <strong>C3 \u4f4d<\/strong>\u9644\u8fd1\u3002<\/li>\n<li style=\"margin:6px 0;\">\u777e\u916e\u7684 <strong>A \u73af<\/strong>\u76f4\u63a5\u53c2\u4e0e anti-IC \u7ed3\u5408\u2014\u2014\u5373\u201c\u5c0f\u5206\u5b50\u672c\u8eab\u7684\u67d0\u4e00\u6bb5\u201d\u5c31\u662f\u754c\u9762\u7684\u4e00\u90e8\u5206\u3002<\/li>\n<\/ul>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u4e94\u3001\u6280\u672f\u98ce\u9669<\/h2>\n<ul style=\"padding-left:22px;margin:12px 0;\">\n<li style=\"margin:6px 0;\"><strong>anti-IC \u7684\u4eb2\u548c\u529b\u51b3\u5b9a\u6210\u8d25<\/strong>\uff0c\u4eb2\u548c\u529b\u4e0d\u591f\u65f6\uff0c<strong>\u975e\u7ade\u4e89\u6cd5\u53ef\u80fd\u53cd\u800c\u4e0d\u5982\u7ade\u4e89\u6cd5\u7075\u654f<\/strong>\uff1b<\/li>\n<li style=\"margin:6px 0;\"><strong>\u4f20\u7edf\u6742\u4ea4\u7624\u8def\u7ebf\u9633\u6027\u514b\u9686\u7387\u4f4e<\/strong>\uff1b<\/li>\n<li style=\"margin:6px 0;\"><strong>ADLib \u4eb2\u548c\u529b\u504f\u4f4e<\/strong>\uff0810\u207b\u2077\u201310\u207b\u2078 M\uff09\u9700\u4e8c\u6b21\u6210\u719f\uff1bIgM \u4e94\u805a\u4f53\u7a33\u5b9a\u6027\u5dee\uff1b<\/li>\n<li style=\"margin:6px 0;\"><strong>\u4ea4\u53c9\u53cd\u5e94\u9700\u8bc4\u4f30<\/strong>\uff1a\u777e\u916e\u4e0e DHT \u4ea4\u53c9\u660e\u663e\uff08Eronen 2024\uff1aDHT \u663e\u8457\u3001A4\/DHEA-S \u8f7b\u5fae\uff1b\u53e6\u636e\u62a5\u9053\u777e\u916e\u4e0e DHT \u4ea4\u53c9 7.9%\uff09\uff1b<\/li>\n<li style=\"margin:6px 0;\">\u5373\u4f7f\u5316\u5b66\u4ea4\u8054\uff0c<strong>\u4ecd\u6709\u76f8\u5f53\u6bd4\u4f8b\u4ea7\u7269\u662f\u6297\u72ec\u7279\u578b\u800c\u975e anti-IC<\/strong>\u3002<\/li>\n<\/ul>\n<blockquote style=\"background:#f6f8fb;border-left:4px solid #1f3a5f;margin:14px 0;padding:10px 14px;color:#555;font-size:15px;\"><p>Towbin H, et al. *J Immunol Methods*. 1995;181(2):167-176. \uff5c B\u00e4ckstr\u00f6m I, et al. *Anal Chem*. 2026;98:6620-6626. \uff5c Gao Q, et al. *Food Chem*. 2025. \uff5c Seo H, et al. *Nat Protoc*. 2006;1(3):1502-1506. \uff5c Du K, et al. *ACS Omega*. 2024;9:45688-45705. \uff5c Du K, et al. *Anal Methods*. 2024;16:5357-5371.<\/p><\/blockquote>\n<\/section>\n<p>  <!-- \u6587\u672b\u547c\u544a --><\/p>\n<p style=\"margin:28px 0 8px;color:#1f3a5f;font-weight:bold;font-size:17px;\">\n<p>  <!-- \u5206\u9694\u7ebf --><\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:24px 0;\">\n<p>  <!-- \u5f80\u671f\u70ed\u70b9\u6587\u7ae0\uff08\u6bcf\u671f\u6362\uff09 --><\/p>\n<section style=\"background:#f6f8fb;border-left:4px solid #1f3a5f;padding:14px 16px;margin:0 0 20px;border-radius:0 6px 6px 0;\">\n<p style=\"margin:0 0 10px;font-weight:bold;color:#1f3a5f;font-size:15px;\">\u5f80\u671f\u70ed\u70b9\u6587\u7ae0<\/p>\n<p style=\"margin:6px 0;font-size:14px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5NjIzNDU4NQ==&#038;mid=2247485377&#038;idx=1&#038;sn=4e8e20422bd83cc154d5484b0037f0b0\" style=\"color:#1f6fb8;text-decoration:none;\">\u5927\u5bb6\u597d\uff0c\u6211\u53eb\u9b4f\u5927\u6d77\u3002\uff08\u5168\u6587\u5b8c\u6574\u7248\uff09<\/a><\/p>\n<p style=\"margin:6px 0;font-size:14px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5NjIzNDU4NQ==&#038;mid=2247484400&#038;idx=1&#038;sn=6b384d73a26a9c622c745275a86f59fd\" style=\"color:#1f6fb8;text-decoration:none;\">\u94fe\u9709\u4eb2\u548c\u7d20\u5fae\u7403\u662f\u5982\u4f55\u5236\u5907\u7684\uff1f<\/a><\/p>\n<p style=\"margin:6px 0;font-size:14px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5NjIzNDU4NQ==&#038;mid=2247484362&#038;idx=1&#038;sn=a68382db7d3008165c534d93125633aa\" style=\"color:#1f6fb8;text-decoration:none;\">\u6297\u4f53\u6807\u8bb0\u7528\u751f\u7269\u7d20\uff0c\u4f60\u9009\u5bf9\u4e86\u5417\uff1f<\/a><\/p>\n<p style=\"margin:6px 0;font-size:14px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5NjIzNDU4NQ==&#038;mid=2247484503&#038;idx=1&#038;sn=69c1df88923335f7cdfa9fdcd84bd519\" style=\"color:#1f6fb8;text-decoration:none;\">\u7a7a\u767d\u9650\u3001\u68c0\u51fa\u9650\u3001\u5b9a\u91cf\u9650\uff0c\u4e00\u7bc7\u5c31\u8ba9\u4f60\u660e\u767d\uff01<\/a><\/p>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>\u5c0f\u5206\u5b50\uff0811.5 \u00c5 \u6700\u4f18\uff08Quinton 2010\uff09\u3002 \u534a\u5361\u5df4\u80bc\uff08SEM\uff09\u2014\u201412 \u00c5 \u8d85\u9608\u503c\uff0c16 \u00c5 \u8fbe [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[94],"tags":[],"class_list":["post-420","post","type-post","status-publish","format-standard","hentry","category-94"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf - IVD-STAGE<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf - IVD-STAGE\" \/>\n<meta property=\"og:description\" content=\"\u5c0f\u5206\u5b50\uff0811.5 \u00c5 \u6700\u4f18\uff08Quinton 2010\uff09\u3002 \u534a\u5361\u5df4\u80bc\uff08SEM\uff09\u2014\u201412 \u00c5 \u8d85\u9608\u503c\uff0c16 \u00c5 \u8fbe [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf\/\" \/>\n<meta property=\"og:site_name\" content=\"IVD-STAGE\" \/>\n<meta property=\"article:published_time\" content=\"2026-10-11T23:30:00+00:00\" \/>\n<meta name=\"author\" content=\"\u660e\u8fdc\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u4f5c\u8005\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u660e\u8fdc\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u9884\u8ba1\u9605\u8bfb\u65f6\u95f4\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 \u5206\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/index.php\\\/2026\\\/10\\\/12\\\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/index.php\\\/2026\\\/10\\\/12\\\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\\\/\"},\"author\":{\"name\":\"\u660e\u8fdc\",\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/#\\\/schema\\\/person\\\/18fadc8a347263420d68efc7c3339bb9\"},\"headline\":\"\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf\",\"datePublished\":\"2026-10-11T23:30:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/index.php\\\/2026\\\/10\\\/12\\\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\\\/\"},\"wordCount\":234,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/#\\\/schema\\\/person\\\/641bbe2b033ba19268efa7bb5bf95d57\"},\"articleSection\":[\"\u5de5\u4f5c\u6280\u80fd\"],\"inLanguage\":\"zh-Hans\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.ivd-stage.com\\\/index.php\\\/2026\\\/10\\\/12\\\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/index.php\\\/2026\\\/10\\\/12\\\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\\\/\",\"url\":\"https:\\\/\\\/www.ivd-stage.com\\\/index.php\\\/2026\\\/10\\\/12\\\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\\\/\",\"name\":\"\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf - IVD-STAGE\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/#website\"},\"datePublished\":\"2026-10-11T23:30:00+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/index.php\\\/2026\\\/10\\\/12\\\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\\\/#breadcrumb\"},\"inLanguage\":\"zh-Hans\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.ivd-stage.com\\\/index.php\\\/2026\\\/10\\\/12\\\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/index.php\\\/2026\\\/10\\\/12\\\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\\\/\\\/www.ivd-stage.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/#website\",\"url\":\"https:\\\/\\\/www.ivd-stage.com\\\/\",\"name\":\"IVD-STAGE\",\"description\":\"\u4e13\u6ce8\u4e8eIVD\u884c\u4e1a\u8d44\u8baf\u548c\u6280\u672f\u5206\u4eab\uff01\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/#\\\/schema\\\/person\\\/641bbe2b033ba19268efa7bb5bf95d57\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.ivd-stage.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"zh-Hans\"},{\"@type\":[\"Person\",\"Organization\"],\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/#\\\/schema\\\/person\\\/641bbe2b033ba19268efa7bb5bf95d57\",\"name\":\"Wu Yaoping\",\"pronouns\":\"they\\\/them\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/wp-content\\\/uploads\\\/2026\\\/03\\\/cropped-cropped-\u5fae\u4fe1\u56fe\u7247_20260303120909_55_2.jpg\",\"url\":\"https:\\\/\\\/www.ivd-stage.com\\\/wp-content\\\/uploads\\\/2026\\\/03\\\/cropped-cropped-\u5fae\u4fe1\u56fe\u7247_20260303120909_55_2.jpg\",\"contentUrl\":\"https:\\\/\\\/www.ivd-stage.com\\\/wp-content\\\/uploads\\\/2026\\\/03\\\/cropped-cropped-\u5fae\u4fe1\u56fe\u7247_20260303120909_55_2.jpg\",\"width\":512,\"height\":423,\"caption\":\"Wu Yaoping\"},\"logo\":{\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/wp-content\\\/uploads\\\/2026\\\/03\\\/cropped-cropped-\u5fae\u4fe1\u56fe\u7247_20260303120909_55_2.jpg\"},\"sameAs\":[\"http:\\\/\\\/www.ivd-stage.com\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.ivd-stage.com\\\/#\\\/schema\\\/person\\\/18fadc8a347263420d68efc7c3339bb9\",\"name\":\"\u660e\u8fdc\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/831d0defb8da6fcbb7a6d95b3844ee3c1334227154730dd289de93d0559b5ef9?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/831d0defb8da6fcbb7a6d95b3844ee3c1334227154730dd289de93d0559b5ef9?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/831d0defb8da6fcbb7a6d95b3844ee3c1334227154730dd289de93d0559b5ef9?s=96&d=mm&r=g\",\"caption\":\"\u660e\u8fdc\"},\"url\":\"https:\\\/\\\/www.ivd-stage.com\\\/index.php\\\/author\\\/ming-yuan\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf - IVD-STAGE","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf\/","og_locale":"zh_CN","og_type":"article","og_title":"\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf - IVD-STAGE","og_description":"\u5c0f\u5206\u5b50\uff0811.5 \u00c5 \u6700\u4f18\uff08Quinton 2010\uff09\u3002 \u534a\u5361\u5df4\u80bc\uff08SEM\uff09\u2014\u201412 \u00c5 \u8d85\u9608\u503c\uff0c16 \u00c5 \u8fbe [&hellip;]","og_url":"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf\/","og_site_name":"IVD-STAGE","article_published_time":"2026-10-11T23:30:00+00:00","author":"\u660e\u8fdc","twitter_card":"summary_large_image","twitter_misc":{"\u4f5c\u8005":"\u660e\u8fdc","\u9884\u8ba1\u9605\u8bfb\u65f6\u95f4":"1 \u5206"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\/#article","isPartOf":{"@id":"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\/"},"author":{"name":"\u660e\u8fdc","@id":"https:\/\/www.ivd-stage.com\/#\/schema\/person\/18fadc8a347263420d68efc7c3339bb9"},"headline":"\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf","datePublished":"2026-10-11T23:30:00+00:00","mainEntityOfPage":{"@id":"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\/"},"wordCount":234,"commentCount":0,"publisher":{"@id":"https:\/\/www.ivd-stage.com\/#\/schema\/person\/641bbe2b033ba19268efa7bb5bf95d57"},"articleSection":["\u5de5\u4f5c\u6280\u80fd"],"inLanguage":"zh-Hans","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\/","url":"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\/","name":"\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf - IVD-STAGE","isPartOf":{"@id":"https:\/\/www.ivd-stage.com\/#website"},"datePublished":"2026-10-11T23:30:00+00:00","breadcrumb":{"@id":"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\/#breadcrumb"},"inLanguage":"zh-Hans","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.ivd-stage.com\/index.php\/2026\/10\/12\/%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%ef%bc%9a%e6%8a%97%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e6%8a%97%e4%bd%93%e7%9a%84%e5%88%b6%e5%a4%87%e8%b7%af%e7%ba%bf\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/www.ivd-stage.com\/"},{"@type":"ListItem","position":2,"name":"\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\uff1a\u6297\u514d\u75ab\u590d\u5408\u7269\u6297\u4f53\u7684\u5236\u5907\u8def\u7ebf"}]},{"@type":"WebSite","@id":"https:\/\/www.ivd-stage.com\/#website","url":"https:\/\/www.ivd-stage.com\/","name":"IVD-STAGE","description":"\u4e13\u6ce8\u4e8eIVD\u884c\u4e1a\u8d44\u8baf\u548c\u6280\u672f\u5206\u4eab\uff01","publisher":{"@id":"https:\/\/www.ivd-stage.com\/#\/schema\/person\/641bbe2b033ba19268efa7bb5bf95d57"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.ivd-stage.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"zh-Hans"},{"@type":["Person","Organization"],"@id":"https:\/\/www.ivd-stage.com\/#\/schema\/person\/641bbe2b033ba19268efa7bb5bf95d57","name":"Wu Yaoping","pronouns":"they\/them","image":{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"https:\/\/www.ivd-stage.com\/wp-content\/uploads\/2026\/03\/cropped-cropped-\u5fae\u4fe1\u56fe\u7247_20260303120909_55_2.jpg","url":"https:\/\/www.ivd-stage.com\/wp-content\/uploads\/2026\/03\/cropped-cropped-\u5fae\u4fe1\u56fe\u7247_20260303120909_55_2.jpg","contentUrl":"https:\/\/www.ivd-stage.com\/wp-content\/uploads\/2026\/03\/cropped-cropped-\u5fae\u4fe1\u56fe\u7247_20260303120909_55_2.jpg","width":512,"height":423,"caption":"Wu Yaoping"},"logo":{"@id":"https:\/\/www.ivd-stage.com\/wp-content\/uploads\/2026\/03\/cropped-cropped-\u5fae\u4fe1\u56fe\u7247_20260303120909_55_2.jpg"},"sameAs":["http:\/\/www.ivd-stage.com"]},{"@type":"Person","@id":"https:\/\/www.ivd-stage.com\/#\/schema\/person\/18fadc8a347263420d68efc7c3339bb9","name":"\u660e\u8fdc","image":{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"https:\/\/secure.gravatar.com\/avatar\/831d0defb8da6fcbb7a6d95b3844ee3c1334227154730dd289de93d0559b5ef9?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/831d0defb8da6fcbb7a6d95b3844ee3c1334227154730dd289de93d0559b5ef9?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/831d0defb8da6fcbb7a6d95b3844ee3c1334227154730dd289de93d0559b5ef9?s=96&d=mm&r=g","caption":"\u660e\u8fdc"},"url":"https:\/\/www.ivd-stage.com\/index.php\/author\/ming-yuan\/"}]}},"jetpack_publicize_connections":[],"jetpack_likes_enabled":true,"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/www.ivd-stage.com\/index.php\/wp-json\/wp\/v2\/posts\/420","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ivd-stage.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ivd-stage.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ivd-stage.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ivd-stage.com\/index.php\/wp-json\/wp\/v2\/comments?post=420"}],"version-history":[{"count":1,"href":"https:\/\/www.ivd-stage.com\/index.php\/wp-json\/wp\/v2\/posts\/420\/revisions"}],"predecessor-version":[{"id":421,"href":"https:\/\/www.ivd-stage.com\/index.php\/wp-json\/wp\/v2\/posts\/420\/revisions\/421"}],"wp:attachment":[{"href":"https:\/\/www.ivd-stage.com\/index.php\/wp-json\/wp\/v2\/media?parent=420"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ivd-stage.com\/index.php\/wp-json\/wp\/v2\/categories?post=420"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ivd-stage.com\/index.php\/wp-json\/wp\/v2\/tags?post=420"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}