{"id":365,"date":"2026-09-29T15:48:40","date_gmt":"2026-09-29T07:48:40","guid":{"rendered":"https:\/\/www.ivd-stage.com\/?p=365"},"modified":"2026-09-29T15:48:40","modified_gmt":"2026-09-29T07:48:40","slug":"%e6%96%b0%e4%ba%a7%e4%b8%9a%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%e6%b5%8b25-%e7%be%9f%e5%9f%ba%e7%bb%b4%e7%94%9f%e7%b4%a0d%ef%bc%8c%e6%80%a7%e8%83%bd%e5%b0%b1%e6%98%af%e8%bf%99","status":"publish","type":"post","link":"https:\/\/www.ivd-stage.com\/index.php\/2026\/09\/29\/%e6%96%b0%e4%ba%a7%e4%b8%9a%e5%b0%8f%e5%88%86%e5%ad%90%e5%a4%b9%e5%bf%83%e6%b3%95%e6%b5%8b25-%e7%be%9f%e5%9f%ba%e7%bb%b4%e7%94%9f%e7%b4%a0d%ef%bc%8c%e6%80%a7%e8%83%bd%e5%b0%b1%e6%98%af%e8%bf%99\/","title":{"rendered":"\u65b0\u4ea7\u4e1a\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\u6d4b25-\u7f9f\u57fa\u7ef4\u751f\u7d20D\uff0c\u6027\u80fd\u5c31\u662f\u8fd9\u4e48\u725b\uff01"},"content":{"rendered":"<p><!-- IVD-STAGE \u516c\u4f17\u53f7\u6392\u7248\u6a21\u677f\uff08\u5185\u8054\u6837\u5f0f\uff0c\u517c\u5bb9\u5fae\u4fe1\uff09\n\u53d8\u91cf\u5360\u4f4d\u7b26\uff08\u63a8\u9001\u811a\u672c\u4f1a\u66ff\u6362\uff09\uff1a\n  \u65b0\u4ea7\u4e1a\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\u6d4b25-\u7f9f\u57fa\u7ef4\u751f\u7d20D\uff0c\u6027\u80fd\u5c31\u662f\u8fd9\u4e48\u725b\uff01        \u6587\u7ae0\u6807\u9898\n  [CONTENT]        \u6b63\u6587 HTML\uff08\u7531 markdown \u8f6c\u6362\u5f97\u5230\uff09\n           \u53d1\u5e03\u65e5\u671f 2026\u5e748\u670811\u65e5\n      \u6587\u672b\u7f72\u540d\/\u547c\u544a\uff08\u53ef\u9009\uff09\n  {{RELATED_1..4}} \u5f80\u671f\u63a8\u8350 \u6807\u9898|\u94fe\u63a5 \uff08\u6bcf\u671f\u6362\uff0c\u53ef\u5c11\u586b\uff09\n--><\/p>\n<div style=\"font-family:-apple-system,'PingFang SC','Microsoft YaHei',sans-serif;color:#2b2b2b;font-size:15px;line-height:2;letter-spacing:0.5px;\">\n<p>  <!-- \u6b63\u6587 --><\/p>\n<section style=\"margin:0;padding:16px 8px;background:#f7f8fa;border-radius:8px;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u65b0\u4ea7\u4e1a\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\u6d4b25-\u7f9f\u57fa\u7ef4\u751f\u7d20D\uff0c\u6027\u80fd\u5c31\u662f\u8fd9\u4e48\u725b\uff01<\/h2>\n<blockquote style=\"background:#f6f8fb;border-left:4px solid #1f3a5f;margin:14px 0;padding:10px 14px;color:#555;font-size:15px;\"><p>200 \u4efd\u8840\u6e05\u53cc\u76f2\u9001\u68c0\uff0c\u540c\u4e00\u4efd\u6837\u672c\u5728\u4e94\u53f0\u5316\u5b66\u53d1\u5149\u514d\u75ab\u5206\u6790\uff08CLIA\uff09\u5e73\u53f0\u4e0a\u6d4b 25-\u7f9f\u57fa\u7ef4\u751f\u7d20D\uff0c\u4ee5\u6db2\u76f8\u8272\u8c31\u4e32\u8054\u8d28\u8c31\uff08LC-MS\/MS\uff09\u4e3a\u53c2\u8003\u65b9\u6cd5\u3002\u65b0\u4ea7\u4e1a\u7684\u56fd\u4ea7\u975e\u7ade\u4e89\u6297\u514d\u75ab\u590d\u5408\u7269\u6cd5\uff08NACA\uff09\u5e73\u5747\u76f8\u5bf9\u504f\u501a <strong>\u22123.84%<\/strong>\uff0c\u7d22\u7075 +3.66%\u3001\u8d1d\u514b\u66fc +5.21%\u3001\u7f57\u6c0f +20.29%\uff0c\u4e07\u6cf0 <strong>+61.75%<\/strong>\u3002<\/p><\/blockquote>\n<p style=\"margin:14px 0;text-align:justify;\">![[Pasted image 20260929154418.png]]<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u600e\u4e48\u6bd4<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">200 \u4efd\u8840\u6e05\uff0c93 \u540d\u7537\u6027\u3001107 \u540d\u5973\u6027\uff0c\u5e74\u9f84 1 \u5230 88 \u5c81\uff0c\u6bcf\u4efd\u6837\u672c\u5206\u4e09\u7ba1\u4e8e \u221280\u2103 \u51bb\u5b58\u3002\u5efa\u76f2\u8868\u628a\u6837\u672c\u7f16\u53f7\u548c\u968f\u673a\u7801\u5206\u5f00\uff0c\u5efa\u76f2\u89e3\u76f2\u7531\u4e0d\u540c\u7684\u4eba\u505a\uff0c\u64cd\u4f5c\u8005\u4e0d\u53c2\u4e0e\u76f2\u6cd5\uff0c\u4e94\u53f0\u4eea\u5668\u540c\u4e00\u5929\u6d4b\u5b8c\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u4e94\u53f0\u4eea\u5668\u5206\u522b\u662f\u65b0\u4ea7\u4e1a Maglumi X8\u3001\u4e07\u6cf0 Wan200\u3001\u8d1d\u514b\u66fc DXI800\u3001\u7d22\u7075 LIAISON XL\u3001\u7f57\u6c0f Cobas e602\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u53c2\u8003\u65b9\u6cd5 LC-MS\/MS \u7531\u5e7f\u5dde\u91d1\u57df\u5b8c\u6210\uff0c\u6821\u51c6\u54c1\u6eaf\u6e90 NIST \u7684 SRM 2972\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u72b6\u6001\u5206\u7ea7\u7528 2025 \u5e74\u4e24\u4efd\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\u7684\u53e3\u5f84\uff0c\u4f4e\u4e8e 50 nmol\/L \u7f3a\u4e4f\uff0c50 \u5230 75 \u4e0d\u8db3\uff0c75 \u5230 150 \u5145\u8db3\uff0c\u8d85\u8fc7 150 \u4e3a\u8fc7\u91cf\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u7cbe\u5bc6\u5ea6<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u91cd\u590d\u6027\u53d8\u5f02\u7cfb\u6570\uff08CV\uff09\uff1a\u65b0\u4ea7\u4e1aNACA <strong>1.13% \u5230 2.75%<\/strong>\uff0c\u53e6\u5916\u56db\u5bb6 3.04% \u5230 6.60%\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u5ba4\u5185 CV\uff1a\u65b0\u4ea7\u4e1aNACA <strong>1.59% \u5230 2.58%<\/strong>\uff0c\u53e6\u5916\u56db\u5bb6 5.01% \u5230 10.52%\uff0c\u6700\u9ad8\u7684\u662f\u8d1d\u514b\u66fc\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u6b63\u786e\u5ea6\uff1a\u65b0\u4ea7\u4e1aNACA \u76f8\u5bf9\u504f\u501a <strong>1.01% \u5230 1.76%<\/strong>\uff0c\u4e94\u53f0\u91cc\u6700\u5c0f\uff1b\u4e07\u6cf0 \u22123.85% \u5230 2.32%\u3001\u8d1d\u514b\u66fc 6.50% \u5230 6.70%\u3001\u7d22\u7075 \u22121.80% \u5230 6.81%\u3001\u7f57\u6c0f \u22129.38% \u5230 7.88%\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u504f\u501a<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u4e0e LC-MS\/MS \u6bd4\u8f83\u5e73\u5747\u76f8\u5bf9\u504f\u501a\uff08199 \u5bf9\u6837\u672c\uff0c\u5254\u6389\u4e00\u4efd 498 nmol\/L\u3001\u8d85\u51fa\u591a\u6570\u5e73\u53f0\u7ebf\u6027\u8303\u56f4\uff09\uff0c\u65b0\u4ea7\u4e1a NACA <strong>\u22123.84%<\/strong>\u3001\u7d22\u7075 <strong>+3.66%<\/strong>\u3001\u8d1d\u514b\u66fc <strong>+5.21%<\/strong>\u3001\u7f57\u6c0f <strong>+20.29%<\/strong>\u3001\u4e07\u6cf0 <strong>+61.75%<\/strong>\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u56fd\u9645\u901a\u884c\u7684\u4e34\u5e8a\u5141\u8bb8\u9650\u662f \u00b125%\u3002\u524d\u4e09\u53f0\u7a33\u7a33\u5728\u9650\u5185\uff1b\u7f57\u6c0f\u5361\u5728\u9650\u5185\u4f46\u6548\u5e94\u91cf r=0.816\uff0c\u662f\u7cfb\u7edf\u6027\u504f\u79fb\uff1b<strong>\u4e07\u6cf0\u8d85\u51fa\u9650\u503c\u4e00\u500d\u591a<\/strong>\uff0cBland-Altman \u4e00\u81f4\u6027\u754c\u9650\u5bbd\u5230 \u2212124.28 \u5230 226.82 nmol\/L\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u4e00\u81f4\u6027<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">Passing-Bablok \u56de\u5f52\uff0c\u65b0\u4ea7\u4e1a \u7684\u65b9\u7a0b\u662f <strong>y = \u22121.24 + 0.99x<\/strong>\uff0c\u659c\u7387 0.99\uff0895%CI 0.96 \u5230 1.03\uff09\u5305\u542b 1\uff0c\u622a\u8ddd \u22121.24\uff0895%CI \u22123.49 \u5230 0.65\uff09\u5305\u542b 0\u2014\u2014\u6bd4\u4f8b\u504f\u5dee\u548c\u56fa\u5b9a\u504f\u5dee\u90fd\u4e0d\u663e\u8457\u3002Spearman \u03c1=0.969\uff0c\u7ec4\u5185\u76f8\u5173\u7cfb\u6570\uff08ICC\uff09<strong>0.9584<\/strong>\uff0895%CI 0.9453 \u5230 0.9684\uff09\uff0c\u6309 ICC \u8bc4\u7ea7\u5c5e\u4e8e&#8221;\u4f18\u79c0&#8221;\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u53e6\u5916\u56db\u53f0\uff1a\u8d1d\u514b\u66fc\u659c\u7387 1.14\u3001\u7d22\u7075 1.11\uff0c\u7f6e\u4fe1\u533a\u95f4\u90fd\u6392\u9664 1\uff0c\u76f8\u5f53\u4e8e<strong>\u7cfb\u7edf\u6027\u9ad8\u4f30 11% \u5230 14%<\/strong>\uff1b\u7f57\u6c0f\u659c\u7387 1.16\u3001\u622a\u8ddd 4.00\uff0c\u4f4e\u6d53\u5ea6\u6709\u6b63\u56fa\u5b9a\u504f\u501a\uff1b\u4e07\u6cf0\u659c\u7387 <strong>1.99<\/strong>\u3001ICC \u53ea\u6709 <strong>0.4669<\/strong>\uff0c\u843d\u5728&#8221;\u4e0d\u53ef\u63a5\u53d7&#8221;\u533a\u95f4\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u5206\u6863<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">\u4ee5 LC-MS\/MS \u4e3a\u57fa\u51c6\u7684 45 \u4f8b\u7f3a\u4e4f\u300150 \u4f8b\u4e0d\u8db3\u300189 \u4f8b\u5145\u8db3\u300116 \u4f8b\u8fc7\u91cf\u3002<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">\u6b63\u786e\u5206\u6863\u7387\uff0c\u65b0\u4ea7\u4e1aNACA \u603b\u4f53 <strong>87.0%<\/strong>\uff0c\u7f3a\u4e4f\u6863 <strong>97.8%<\/strong>\u3001\u4e0d\u8db3\u6863 78.0%\u3001\u5145\u8db3\u6863 88.8%\u3001\u8fc7\u91cf\u6863 75.0%\uff1b\u7d22\u7075 81.0%\u3001\u8d1d\u514b\u66fc 73.0%\u3001\u7f57\u6c0f 70.0%\u3001\u4e07\u6cf0 <strong>50.0%<\/strong>\uff0c\u4e07\u6cf0\u4e0d\u8db3\u6863\u53ea\u5bf9\u4e86 28.0%\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<h2 style=\"color:#1f3a5f;font-size:16px;font-weight:bold;margin:20px 0 10px;\">\u51b3\u7b56\u9650<\/h2>\n<p style=\"margin:14px 0;text-align:justify;\">50 nmol\/L \u8fd9\u6761\u7f3a\u4e4f\u5224\u5b9a\u7ebf\u4e0a\uff0c\u65b0\u4ea7\u4e1a\u504f\u501a <strong>\u22126.2%<\/strong>\uff0c\u7d22\u7075\u5728 \u00b15% \u5185\uff0c\u8d1d\u514b\u66fc \u221212.4%\uff0c\u7f57\u6c0f <strong>+17.3%<\/strong>\uff0c\u4e07\u6cf0 <strong>+54.5%<\/strong>\uff1b<\/p>\n<p style=\"margin:14px 0;text-align:justify;\">75 nmol\/L \u5145\u8db3\u7ebf\u4e0a\uff0c\u65b0\u4ea7\u4e1a \u53ea\u6709 <strong>+0.4%<\/strong>\u3002\u6309 CLSI \u7684\u53ef\u63a5\u53d7\u6807\u51c6\uff08\u504f\u5dee \u2264\u00b14.8 nmol\/L \u6216\u76f8\u5bf9\u504f\u501a \u22645%\uff09\uff0c\u4e24\u4e2a\u51b3\u7b56\u9650\u4e0a\u90fd\u8fc7\u5f97\u53bb\u7684\u53ea\u6709 \u65b0\u4ea7\u4e1aNACA \u548c\u7d22\u7075\u3002<\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:22px 0;\">\n<p style=\"margin:14px 0;text-align:justify;\"><strong>\u5c0f\u5206\u5b50\u975e\u7ade\u4e89\u6cd5\uff0c\u56fd\u4ea7\u5c31\u662f\u725b\u3002<\/strong><\/p>\n<blockquote style=\"background:#f6f8fb;border-left:4px solid #1f3a5f;margin:14px 0;padding:10px 14px;color:#555;font-size:15px;\"><p>Zhong J, Huang B, Lin A, et al. Evaluation of a new non-competitive chemiluminescent immunoassay for 25-OH vitamin D measurement. *Diagnosis (Berl)*. 2026. DOI: 10.1515\/dx-2026-0094<\/p><\/blockquote>\n<\/section>\n<p>  <!-- \u6587\u672b\u547c\u544a --><\/p>\n<p style=\"margin:28px 0 8px;color:#1f3a5f;font-weight:bold;font-size:17px;\">\n<p>  <!-- \u5206\u9694\u7ebf --><\/p>\n<p style=\"border-top:1px solid #e3e8ef;margin:24px 0;\">\n<p>  <!-- \u5f80\u671f\u70ed\u70b9\u6587\u7ae0\uff08\u6bcf\u671f\u6362\uff09 --><\/p>\n<section style=\"background:#f6f8fb;border-left:4px solid #1f3a5f;padding:14px 16px;margin:0 0 20px;border-radius:0 6px 6px 0;\">\n<p style=\"margin:0 0 10px;font-weight:bold;color:#1f3a5f;font-size:15px;\">\u5f80\u671f\u70ed\u70b9\u6587\u7ae0<\/p>\n<p style=\"margin:6px 0;font-size:14px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5NjIzNDU4NQ==&#038;mid=2247485377&#038;idx=1&#038;sn=4e8e20422bd83cc154d5484b0037f0b0\" style=\"color:#1f6fb8;text-decoration:none;\">\u5927\u5bb6\u597d\uff0c\u6211\u53eb\u9b4f\u5927\u6d77\u3002\uff08\u5168\u6587\u5b8c\u6574\u7248\uff09<\/a><\/p>\n<p style=\"margin:6px 0;font-size:14px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5NjIzNDU4NQ==&#038;mid=2247484400&#038;idx=1&#038;sn=6b384d73a26a9c622c745275a86f59fd\" style=\"color:#1f6fb8;text-decoration:none;\">\u94fe\u9709\u4eb2\u548c\u7d20\u5fae\u7403\u662f\u5982\u4f55\u5236\u5907\u7684\uff1f<\/a><\/p>\n<p style=\"margin:6px 0;font-size:14px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5NjIzNDU4NQ==&#038;mid=2247484362&#038;idx=1&#038;sn=a68382db7d3008165c534d93125633aa\" style=\"color:#1f6fb8;text-decoration:none;\">\u6297\u4f53\u6807\u8bb0\u7528\u751f\u7269\u7d20\uff0c\u4f60\u9009\u5bf9\u4e86\u5417\uff1f<\/a><\/p>\n<p style=\"margin:6px 0;font-size:14px;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5NjIzNDU4NQ==&#038;mid=2247484503&#038;idx=1&#038;sn=69c1df88923335f7cdfa9fdcd84bd519\" style=\"color:#1f6fb8;text-decoration:none;\">\u7a7a\u767d\u9650\u3001\u68c0\u51fa\u9650\u3001\u5b9a\u91cf\u9650\uff0c\u4e00\u7bc7\u5c31\u8ba9\u4f60\u660e\u767d\uff01<\/a><\/p>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>\u65b0\u4ea7\u4e1a\u5c0f\u5206\u5b50\u5939\u5fc3\u6cd5\u6d4b25-\u7f9f\u57fa\u7ef4\u751f\u7d20D\uff0c\u6027\u80fd\u5c31\u662f\u8fd9\u4e48\u725b\uff01 200 \u4efd\u8840\u6e05\u53cc\u76f2\u9001\u68c0\uff0c\u540c\u4e00\u4efd\u6837\u672c\u5728\u4e94\u53f0\u5316\u5b66\u53d1\u5149\u514d\u75ab [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[7],"tags":[],"class_list":["post-365","post","type-post","status-publish","format-standard","hentry","category-7"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - 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