{"id":186,"date":"2026-07-31T09:00:00","date_gmt":"2026-07-31T01:00:00","guid":{"rendered":"https:\/\/www.ivd-stage.com\/?p=186"},"modified":"2026-07-30T21:05:56","modified_gmt":"2026-07-30T13:05:56","slug":"t%e7%ba%bf%e6%b6%88%e5%a4%b1%e4%ba%86%ef%bc%8c%e5%8f%8d%e8%80%8c%e6%98%af%e9%98%b3%e6%80%a7%ef%bc%9f%e7%ab%9e%e4%ba%89%e5%9e%8blfa%e5%8d%81%e5%b9%b4%e7%bb%bc%e8%bf%b0%ef%bc%8c%e4%b8%80%e6%9c%ac","status":"publish","type":"post","link":"http:\/\/www.ivd-stage.com\/index.php\/2026\/07\/31\/t%e7%ba%bf%e6%b6%88%e5%a4%b1%e4%ba%86%ef%bc%8c%e5%8f%8d%e8%80%8c%e6%98%af%e9%98%b3%e6%80%a7%ef%bc%9f%e7%ab%9e%e4%ba%89%e5%9e%8blfa%e5%8d%81%e5%b9%b4%e7%bb%bc%e8%bf%b0%ef%bc%8c%e4%b8%80%e6%9c%ac\/","title":{"rendered":"T\u7ebf\u6d88\u5931\u4e86\uff0c\u53cd\u800c\u662f\u9633\u6027\uff1f\u7ade\u4e89\u578bLFA\u5341\u5e74\u7efc\u8ff0\uff0c\u4e00\u672c\u5c0f\u5206\u5b50\u5feb\u68c0\u7684\u8bbe\u8ba1\u5723\u7ecf"},"content":{"rendered":"<div style=\"font-family:-apple-system,'PingFang SC','Microsoft YaHei',sans-serif;color:#2b2b2b;font-size:15px;line-height:1.8;max-width:680px;margin:0 auto;\">\n<section>\n<h3>\u7ade\u4e89\u6cd5\u514d\u75ab\u4fa7\u5411\u5c42\u6790\u5341\u5e74\u7efc\u8ff0\uff0c\u4e00\u672c\u5c0f\u5206\u5b50\u68c0\u6d4b\u7684\u8bbe\u8ba1\u5723\u7ecf<\/h3>\n<blockquote>\n<p>Pedreira-Rinc\u00f3n J et al. *Lab Chip*. 2025;25(11):2578-2608. DOI: https:\/\/doi.org\/10.1039\/D4LC01075B<\/p>\n<\/blockquote>\n<p>\u7ade\u4e89\u6cd5\u7684\u903b\u8f91\u8ddf\u5939\u5fc3\u6cd5\uff08sandwich assay\uff09\u662f\u53cd\u7684\u2014\u2014<strong>T\u7ebf\u6d88\u5931 = \u9633\u6027\uff0c\u4e24\u6839\u7ebf\u90fd\u51fa\u6765 = \u9634\u6027<\/strong>\u3002\u8fd9\u4e2a\u53cd\u76f4\u89c9\u7684\u4fe1\u53f7\u8f93\u51fa\u662f\u65b0\u5165\u95e8\u7814\u53d1\u4eba\u5458\u8e29\u8fc7\u7684\u7b2c\u4e00\u4e2a\u5751\uff0c\u4e5f\u662f\u7ec8\u7aef\u7528\u6237\u6700\u5927\u7684\u56f0\u60d1\u6765\u6e90\u3002<\/p>\n<p>\u8fd9\u7bc7\u53d1\u8868\u5728Lab Chip\u4e0a\u7684\u7efc\u8ff0\u628a\u7ade\u4e89\u578bLFA\u4ece\u7406\u8bba\u6a21\u578b\u5230\u7528\u6237\u4f53\u9a8c\uff0c\u51e0\u4e4e\u5b8c\u5168\u8986\u76d6\u3002<\/p>\n<hr>\n<h2>\u4e09\u79cd\u7ade\u4e89\u683c\u5f0f\uff0c\u5404\u6709\u5404\u7684\u4f5c\u7528<\/h2>\n<p>\u7efc\u8ff0\u628a\u7ade\u4e89\u578bLFA\u5206\u6210\u4e09\u7c7b\uff1a<\/p>\n<p><strong>\u76f4\u63a5\u7ade\u4e89<\/strong>\u2014\u2014\u9776\u7269\u8d28\u7684\u5929\u7136\u6216\u91cd\u7ec4\u6297\u539f\u4f5c\u4e3a\u7ade\u4e89\u6297\u539f\u6807\u8bb0\u5728\u63a2\u9488\u4e0a\uff0c\u548c\u6837\u54c1\u4e2d\u7684\u9776\u7269\u8d28\u62a2\u7ed3\u5408\u4f4d\u3002T\u7ebf\u4fe1\u53f7\u8d8a\u5f31\uff0c\u9776\u7269\u8d28\u8d8a\u591a\u3002\u8fd9\u662f\u6700\u7ecf\u5178\u7684\u65b9\u5f0f\u3002<\/p>\n<p><strong>\u95f4\u63a5\u7ade\u4e89<\/strong>\u2014\u2014\u6297\u539f\u56fa\u5b9a\u5728\u819c\u4e0a\u505aT\u7ebf\uff0c\u6837\u54c1\u4e2d\u7684\u9776\u7269\u8d28\u4e0e\u6807\u8bb0\u6297\u4f53\u7ed3\u5408\u540e\u6d41\u8fc7T\u7ebf\uff0c\u9776\u6807\u8d8a\u591a\uff0c\u88abT\u7ebf\u622a\u7559\u7684\u6297\u4f53\u8d8a\u5c11\uff0c\u4fe1\u53f7\u8d8a\u5f31\u3002<\/p>\n<p><strong>\u975e\u6807\u51c6\u65b9\u5f0f<\/strong>\u2014\u2014\u5305\u62ec\u53cd\u5411\u4fe1\u53f7\u3001\u53cc\u7ade\u4e89\u5939\u5fc3\u7b49\uff0c\u9002\u7528\u4e8e\u7279\u6b8a\u573a\u666f\uff08\u5982\u8d85\u5c0f\u5206\u5b50\u3001\u53cc\u8868\u4f4d\u9776\u6807\uff0c\u6bd4\u8f83\u5c11\u89c1\uff09\u3002<\/p>\n<hr>\n<h2>\u7406\u8bba\u5efa\u6a21<\/h2>\n<p>\u7efc\u8ff0\u7528\u4e00\u6574\u7ae0\u8bb2\u5efa\u6a21\uff0c\u5efa\u6a21\u5206\u4e24\u6761\u8def\uff1a<\/p>\n<ul>\n<li>**\u89e3\u6790\u6a21\u578b**\uff1a\u7528\u65b9\u7a0b\u63cf\u8ff0\u7cfb\u7edf\u3002\u6700\u65e9\u53ef\u8ffd\u6eaf\u5230 Qian &#038; Bau \u57282000\u5e74\u4ee3\u521d\u5efa\u7acb\u7684\u5e73\u8861\u6001\u6a21\u578b\u3002Sotnikov \u56e2\u961f\u540e\u6765\u505a\u4e86\u6539\u8fdb\uff0c\u8003\u8651\u4e86LFA\u7684\u975e\u5e73\u8861\u7279\u6027\u3002<\/li>\n<li>**\u6570\u503c\u6a21\u578b**\uff1a\u6b65\u8fdb\u5f0f\u8ba1\u7b97\uff0c\u80fd\u7eb3\u5165\u66f4\u591a\u53c2\u6570\uff08\u6d41\u901f\u3001\u591a\u4ef7\u7ed3\u5408\u3001\u7eb3\u7c73\u9897\u7c92\u8d1f\u8f7d\u91cf\u7b49\uff0c\u66f4\u8d34\u8fd1\u5b9e\u9a8c\u5e38\u89c4\u3002<\/li>\n<\/ul>\n<p>\u5148\u8dd1\u6a21\u578b\u627e\u5230\u6700\u4f18\u53c2\u6570\u7a97\u53e3\uff0c\u518d\u8fdb\u5b9e\u9a8c\u9a8c\u8bc1\uff0c\u80fd\u7701\u4e0d\u5c11\u65f6\u95f4\u3002<\/p>\n<hr>\n<h2>T\u7ebf\u4e0a\u7684\u5173\u952e\u5206\u5b50<\/h2>\n<p>\u7ade\u4e89\u6297\u539f\u7684\u9009\u62e9\u76f4\u63a5\u51b3\u5b9a\u65b9\u6cd5\u5f00\u53d1\u7684\u6210\u8d25\u3002<\/p>\n<ul>\n<li>\u76f4\u63a5\u7ade\u4e89\u7684\u65b9\u5f0f\u4e2d\uff0c\u7ade\u4e89\u6297\u539f\u7684\u4f7f\u7528\u6d53\u5ea6\u8de8\u5ea6**\u4ece5 \u03bcg\/mL\u52303000 \u03bcg\/mL**\uff0c\u8de8\u5ea6600\u500d\uff0c\u8fd9\u53d6\u51b3\u4e8e\u4eb2\u548c\u529b\u548c\u7075\u654f\u5ea6\u9700\u6c42\u3002<\/li>\n<li>\u95f4\u63a5\u7ade\u4e89\u65b9\u5f0f\u4e2d\uff0c\u7ade\u4e89\u6297\u539f\u5206\u5b50\u91cf\u4ece**288 Da\uff08DHEA\uff0c\u8131\u6c22\u8868\u96c4\u916e\uff09\u523067 kDa\uff08HSA\uff0c\u4eba\u8840\u6e05\u767d\u86cb\u767d\uff09**\uff0c\u5927\u591a\u6570\u9700\u8981\u8f7d\u4f53\u86cb\u767d\uff08BSA\u6700\u5e38\u89c1\uff09\u6765\u589e\u5f3a\u7a33\u5b9a\u6027\u6216\u589e\u5f3a\u8868\u9762\u539f\u6027\u3002<\/li>\n<li>\u975e\u6807\u51c6\u65b9\u5f0f\u7684\u7ade\u4e89\u8005\u8bbe\u8ba1\u66f4\u7075\u6d3b\uff0c\u4f46\u66f4\u590d\u6742\u6027\u3002<\/li>\n<\/ul>\n<hr>\n<h2>\u591a\u91cd\u7ade\u4e89<\/h2>\n<p>\u7efc\u8ff0\u8bc6\u522b\u51fa<strong>17\u7bc7<\/strong>\u591a\u91cd\u7ade\u4e89\u578bLFA\u8bba\u6587\u3002\u4e3b\u8981\u53d1\u73b0\uff1a<\/p>\n<ul>\n<li>**\u95f4\u63a5\u7ade\u4e89\u65b9\u5f0f**\u6700\u5e38\u7528\uff0c\u4e3b\u8981\u505a\u53cc\u9776\u6807\u68c0\u6d4b\uff1b<\/li>\n<li>5\u7bc7\u505a\u4e862\u4e2a\u4ee5\u4e0a\u9776\u6807\u7684\u591a\u91cd\u68c0\u6d4b\uff1b<\/li>\n<li>**\u5e94\u7528\u9886\u57df\u9ad8\u5ea6\u96c6\u4e2d\u5728\u98df\u54c1\u5b89\u5168**\u2014\u2014\u6bd2\u7d20\u548c\u6297\u751f\u7d20\u6b8b\u7559\uff0c\u5c11\u6570\u6269\u5c55\u5230\u836f\u7269\u6ee5\u7528\u76d1\u6d4b\u3001\u5065\u5eb7\u6807\u5fd7\u7269\u3001\u9570\u72b6\u7ec6\u80de\u75c5\u8bca\u65ad\uff1b<\/li>\n<\/ul>\n<p>\u591a\u91cd\u68c0\u6d4b\u7684\u6838\u5fc3\u6311\u6218\u5728\u4e8e\u4ea4\u53c9\u53cd\u5e94\u7684\u63a7\u5236\uff0c\u89e3\u51b3\u7b56\u7565\u901a\u5e38\u5305\u62ec\u6297\u4f53\u5de5\u7a0b\u3001\u8ba1\u7b97\u5efa\u6a21\u9884\u6d4b\u4ea4\u53c9\u53cd\u5e94\u3001\u81ea\u7ec4\u88c5\u53d7\u4f53\u7b49\u3002<\/p>\n<hr>\n<h2>\u7528\u6237\u4f53\u9a8c<\/h2>\n<p>\u8fd9\u7bc7\u7efc\u8ff0\u7684\u72ec\u7279\u4e4b\u5904\u5728\u4e8e\u82b1\u4e86\u4e13\u95e8\u7684\u7bc7\u5e45\u6765\u8bb2<strong>\u7528\u6237\u89c6\u89d2<\/strong>\u548c<strong>\u7528\u6237\u4f53\u9a8c<\/strong>\u3002<\/p>\n<p>\u7ade\u4e89\u578bLFA<strong>\u4e24\u6839\u7ebf = \u9634\u6027<\/strong>\uff0c\u4e00\u6839\u7ebf = \u9633\uff0c\u975e\u4e13\u4e1a\u4eba\u5458\u770b\u5230\u4e24\u6839\u7ebf\u4f1a\u672c\u80fd\u4ee5\u4e3a\u662f&#8221;\u9633\u6027&#8221;\u3002<strong>\u5f31\u7ebf\u5224\u8bfb\u96be\u5ea6\u5927<\/strong>\uff0c\u5939\u5fc3\u6cd5\u91cc\u53ea\u8981\u7ebf\u51fa\u73b0\u5c31\u662f\u9633\u6027\uff0c\u7ade\u4e89\u6cd5\u91cc\u8981\u770b\u7684\u662f\u7ebf&#8221;\u6709\u591a\u6de1&#8221;\uff0c\u4eba\u773c\u5f88\u96be\u51c6\u786e\u5224\u65ad\u6e05\u6670\u3002<\/p>\n<hr>\n<h2>ESI\uff1a\u4e00\u5f20\u5341\u5e74\u7684\u53c2\u6570\u603b\u8868<\/h2>\n<p>ESI\uff08Supporting Information\uff09\u628a\u6240\u6709\u5df2\u5927\u90e8\u5206\u4e4b\u524d\u53d1\u8868\u7684\u7ade\u4e89\u578bLFA\u5173\u952e\u53c2\u6570\u6c47\u6210\u4e00\u5f20\u5927\u8868\uff0c\u542b\u9776\u6807\u3001\u53d7\u4f53\u4eb2\u548c\u529b\u3001\u7ade\u4e89\u6297\u539f\u8bbe\u8ba1\u3001\u6807\u8bb0\u7269\u3001\u819c\u6750\u6599\u3001LoD\u3001\u6837\u672c\u57fa\u8d28\u7b49\u3002<strong>\u505a\u65b0\u4ea7\u54c1\u8c03\u7814\u65f6\uff0c\u67e5\u8fd9\u5f20\u8868\u6bd4\u4f60\u4ece\u5934\u641c\u6587\u732e\u5feb\u591a\u5566\u3002<\/strong><\/p>\n<hr>\n<p><strong>\u505a\u5c0f\u5206\u5b50\u5feb\u68c0\u8bd5\u7eb8\u6761\u8fd8\u6ca1\u88ab\u88c1\u7684\u7814\u53d1\u5de5\u7a0b\u5e08\u5feb\u5b66\u8d77\u6765\uff01<\/strong><\/p>\n<blockquote>\n<p>Pedreira-Rinc\u00f3n J et al. *Lab Chip*. 2025;25(11):2578-2608. DOI: https:\/\/doi.org\/10.1039\/D4LC01075B<\/p>\n<\/blockquote>\n<\/section>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u7ade\u4e89\u6cd5\u514d\u75ab\u4fa7\u5411\u5c42\u6790\u5341\u5e74\u7efc\u8ff0\uff0c\u4e00\u672c\u5c0f\u5206\u5b50\u68c0\u6d4b\u7684\u8bbe\u8ba1\u5723\u7ecf Pedreira-Rinc\u00f3n J et al. *La [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[7],"tags":[107,104,105,103,106],"class_list":["post-186","post","type-post","status-publish","format-standard","hentry","category-7","tag-lab-on-a-chip","tag-104","tag-105","tag-lfa","tag-106"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - 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